Protein name:
Coagulation factor VIII;
Alternative:
Procoagulant component;
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Sub Unit:
Interacts with vWF. vWF binding is essential for the stabilization of F8 in circulation.
Function:
Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.
Subcellular Location:
Secreted
extracellular space
Protein Attributes:
50:
MQVELYTCCF | LCLLPFSLSA | TRKYYLGAVE | LSWDYMQSDL | LSALHADTSF |
100:
SSRVPGSLPL | TTSVTYRKTV | FVEFTDDLFN | IAKPRPPWMG | LLGPTIQAEV |
150:
YDTVVIVLKN | MASHPVSLHA | VGVSYWKASE | GAEYEDQTSQ | KEKEDDNVIP |
200:
GESHTYVWQV | LKENGPMASD | PPCLTYSYFS | HVDLVKDLNS | GLIGALLVCK |
250:
EGSLAKERTQ | TLQEFVLLFA | VFDEGKSWHS | ETNASLTQAE | AQHELHTING |
300:
YVNRSLPGLT | VCHKRSVYWH | VIGMGTTPEV | HSIFLEGHTF | LVRNHRQASL |
350:
EISPITFLTA | QTFLMDLGQF | LLFCHIPSHQ | HDGMEAYVKV | DSCPEEPQLR |
400:
MKNNEDKDYD | DGLYDSDMDV | VSFDDDSSSP | FIQIRSVAKK | HPKTWVHYIA |
450:
AEEEDWDYAP | SGPTPNDRSH | KNLYLNNGPQ | RIGKKYKKVR | FVAYTDETFK |
500:
TREAIQYESG | ILGPLLYGEV | GDTLLIIFKN | QASRPYNIYP | HGINYVTPLH |
550:
TGRLPKGVKH | LKDMPILPGE | IFKYKWTVTV | EDGPTKSDPR | CLTRYYSSFI |
600:
NLERDLASGL | IGPLLICYKE | SVDQRGNQMM | SDKRNVILFS | VFDENRSWYL |
650:
TENMQRFLPN | ADVVQPHDPE | FQLSNIMHSI | NGYVFDNLQL | SVCLHEVAYW |
700:
YILSVGAQTD | FLSVFFSGYT | FKHKMVYEDT | LTLFPFSGET | VFMSMENPGL |
750:
WVLGCHNSDF | RNRGMTALLK | VSSCNRNIDD | YYEDTYEDIP | TPLLNENNVI |
800:
KPRSFSQNSR | HPSTKEKQLK | ATTTPENDIE | KIDLQSGERT | QLIKAQSVSS |
850:
SDLLMLLGQN | PTPRGLFLSD | LREATDRADD | HSRGAIERNK | GPPEVASLRP |
900:
ELRHSEDREF | TPEPELQLRL | NENLGTNTTV | ELKKLDLKIS | SSSDSLMTSP |
950:
TIPSDKLAAA | TEKTGSLGPP | NMSVHFNSHL | GTIVFGNNSS | HLIQSGVPLE |
1000:
LSEEDNDSKL | LEAPLMNIQE | SSLRENVLSM | ESNRLFKEER | IRGPASLIKD |
1050:
NALFKVNISS | VKTNRAPVNL | TTNRKTRVAI | PTLLIENSTS | VWQDIMLERN |
1100:
TEFKEVTSLI | HNETFMDRNT | TALGLNHVSN | KTTLSKNVEM | AHQKKEDPVP |
1150:
LRAENPDLSS | SKIPFLPDWI | KTHGKNSLSS | EQRPSPKQLT | SLGSEKSVKD |
1200:
QNFLSEEKVV | VGEDEFTKDT | ELQEIFPNNK | SIFFANLANV | QENDTYNQEK |
1250:
KSPEEIERKE | KLTQENVALP | QAHTMIGTKN | FLKNLFLLST | KQNVAGLEEQ |
1300:
PYTPILQDTR | SLNDSPHSEG | IHMANFSKIR | EEANLEGLGN | QTNQMVERFP |
1350:
STTRMSSNAS | QHVITQRGKR | SLKQPRLSQG | EIKFERKVIA | NDTSTQWSKN |
1400:
MNYLAQGTLT | QIEYNEKEKR | AITQSPLSDC | SMRNHVTIQM | NDSALPVAKE |
1450:
SASPSVRHTD | LTKIPSQHNS | SHLPASACNY | TFRERTSGVQ | EGSHFLQEAK |
1500:
RNNLSLAFVT | LGITEGQGKF | SSLGKSATNQ | PMYKKLENTV | LLQPGLSETS |
1550:
DKVELLSQVH | VDQEDSFPTK | TSNDSPGHLD | LMGKIFLQKT | QGPVKMNKTN |
1600:
SPGKVPFLKW | ATESSEKIPS | KLLGVLAWDN | HYDTQIPSEE | WKSQKKSQTN |
1650:
TAFKRKDTIL | PLGPCENNDS | TAAINEGQDK | PQREAMWAKQ | GEPGRLCSQN |
1700:
PPVSKHHQRE | ITVTTLQPEE | DKFEYDDTFS | IEMKREDFDI | YGDYENQGLR |
1750:
SFQKKTRHYF | IAAVERLWDY | GMSRSPHILR | NRAQSGDVQQ | FKKVVFQEFT |
1800:
DGSFTQPLYR | GELNEHLGLL | GPYIRAEVED | NIVVTFKNQA | SRPYSFYSSL |
1850:
ISYDEDEGQG | AEPRRKFVNP | NETKIYFWKV | QHHMAPTKDE | FDCKAWAYFS |
1900:
DVDLEKDVHS | GLIGPLLICR | SNTLNPAHGR | QVTVQEFALV | FTIFDETKSW |
1950:
YFTENLERNC | RAPCNVQKED | PTLKENFRFH | AINGYVKDTL | PGLVMAQDQK |
2000:
VRWYLLSMGS | NENIHSIHFS | GHVFTVRKKE | EYKMAVYNLY | PGVFETVEML |
2050:
PSQVGIWRIE | CLIGEHLQAG | MSTLFLVYSK | KCQTPLGMAS | GHIRDFQITA |
2100:
SGQYGQWAPK | LARLHYSGSI | NAWSTKDPFS | WIKVDLLAPM | IIHGIMTQGA |
2150:
RQKFSSLYVS | QFIIMYSLDG | NKWHSYRGNS | TGTLMVFFGN | VDSSGIKHNI |
2200:
FNPPIIAQYI | RLHPTHYSIR | STLRMELLGC | DFNSCSMPLG | MESKAISDAQ |
2250:
ITASSYLSSM | LATWSPSQAR | LHLQGRTNAW | RPQANNPKEW | LQVDFRKTMK |
2300:
VTGITTQGVK | SLLISMYVKE | FLISSSQDGH | NWTLFLQNGK | VKVFQGNRDS |
2343:
STPVRNRLEP | PLVARYVRLH | PQSWAHHIAL | RLEVLGCDTQ | QPA

Vaild Sequence:
Related Databases
Uniprot:
FOR
ELISA Kit for Dog Coagulation factor VIII
ELISA Kit for Dog Coagulation factor VIII
ELISA Kit for Dog Coagulation factor VIII
ELISA Kit for Dog Coagulation factor VIII
CLIA Kit for Dog Coagulation factor VIII
CLIA Kit for Dog Coagulation factor VIII
CLIA Kit for Dog Coagulation factor VIII
CLIA Kit for Dog Coagulation factor VIII
Polyclonal Antibody for Dog Coagulation factor VIII
Polyclonal Antibody for Dog Coagulation factor VIII
Polyclonal Antibody for Dog Coagulation factor VIII
Polyclonal Antibody for Dog Coagulation factor VIII
Monoclonal Antibody for Dog Coagulation factor VIII
Monoclonal Antibody for Dog Coagulation factor VIII
Monoclonal Antibody for Dog Coagulation factor VIII
Monoclonal Antibody for Dog Coagulation factor VIII
Protein for Dog Coagulation factor VIII
Protein for Dog Coagulation factor VIII
Protein for Dog Coagulation factor VIII
Protein for Dog Coagulation factor VIII

R&D Technical Data
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Precision
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Recovery
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Linearity
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References
-
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue:
Liver.
-
2.
"Characterization of the canine factor VIII cDNA."
Gordy P.W.
,
Bowen R.A.
Submitted (1998-02) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue:
Kidney.