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Index > Protein center > Fads2(Gene name) > Mouse
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  • Fads2 (Gene name),
  • Fatty acid desaturase 2 (Protein name ),  FADS2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Fads2(Fadsd2);
    Protein name:
    Fatty acid desaturase 2;
    Alternative:
    Delta(6) fatty acid desaturase(D6D;Delta(6) desaturase;Delta-6 desaturase);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleic acid (GLA) (18:3n-6) and stearidonic acid (18:4n-3) respectively and other desaturation steps. Highly unsaturated fatty acids (HUFA) play pivotal roles in many biological functions.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    444
    Sequence:
    50:
    MGKGGNQGEG | STERQAPMPT | FRWEEIQKHN | LRTDRWLVID | RKVYNVTKWS | 
    100:
    QRHPGGHRVI | GHYSGEDATD | AFRAFHLDLD | FVGKFLKPLL | IGELAPEEPS | 
    150:
    LDRGKSSQIT | EDFRALKKTA | EDMNLFKTNH | LFFFLLLSHI | IVMESLAWFI | 
    200:
    LSYFGTGWIP | TLVTAFVLAT | SQAQAGWLQH | DYGHLSVYKK | SIWNHVVHKF | 
    250:
    VIGHLKGASA | NWWNHRHFQH | HAKPNIFHKD | PDIKSLHVFV | LGEWQPLEYG | 
    300:
    KKKLKYLPYN | HQHEYFFLIG | PPLLIPMYFQ | YQIIMTMISR | RDWVDLAWAI | 
    350:
    SYYMRFFYTY | IPFYGILGAL | VFLNFIRFLE | SHWFVWVTQM | NHLVMEIDLD | 
    400:
    HYRDWFSSQL | AATCNVEQSF | FNDWFSGHLN | FQIEHHLFPT | MPRHNLHKIA | 
    444:
    PLVKSLCAKH | GIEYQEKPLL | RALIDIVSSL | KKSGELWLDA | YLHK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    KEGG:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Fatty acid desaturase 2
    Cat.:
    E0400h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Fatty acid desaturase 2
    Cat.:
    E0400r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Fatty acid desaturase 2
    Cat.:
    E0400m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Fatty acid desaturase 2
    Cat.:
    E0400b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Fatty acid desaturase 2
    Cat.:
    U0400b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Fatty acid desaturase 2
    Cat.:
    U0400r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Fatty acid desaturase 2
    Cat.:
    U0400h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Fatty acid desaturase 2
    Cat.:
    U0400m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Fatty acid desaturase 2
    Polyclonal Antibody for Mouse Fatty acid desaturase 2
    Cat.:
    P0400Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Fatty acid desaturase 2
    Cat.:
    P0400Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Fatty acid desaturase 2
    Cat.:
    P0400Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Fatty acid desaturase 2
    Monoclonal Antibody for Mouse Fatty acid desaturase 2
    Monoclonal Antibody for Mouse Fatty acid desaturase 2
    Monoclonal Antibody for Mouse Fatty acid desaturase 2
    Protein for Mouse Fatty acid desaturase 2
    Protein for Mouse Fatty acid desaturase 2
    Protein for Mouse Fatty acid desaturase 2
    Protein for Mouse Fatty acid desaturase 2

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    References
    1. 1.
      "Cloning, expression, and nutritional regulation of the mammalian Delta-6 desaturase."
      Cho H.P. , Nakamura M.T. , Clarke S.D.
      J. Biol. Chem.274:471-477(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;INDUCTION
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Embryo.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Liver.
    4. 4.
      "Dual regulation of mouse Delta(5)- and Delta(6)-desaturase gene expression by SREBP-1 and PPARalpha."
      Matsuzaka T. , Shimano H. , Yahagi N. , Amemiya-Kudo M. , Yoshikawa T. , Hasty A.H. , Tamura Y. , Osuga J. , Okazaki H. , Iizuka Y. , Takahashi A. , Sone H. , Gotoda T. , Ishibashi S. , Yamada N.
      J. Lipid Res.43:107-114(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INDUCTION
      strain: C57BL/6J.
      tissue: Liver.
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