Protein name:
Fas apoptotic inhibitory molecule 3 ;
Alternative:
Regulator of Fas-induced apoptosis Toso ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Subcellular Location:
Membrane
Single-pass membrane protein
Protein Attributes:
50:
MDFWLWPLYF | LPVSGALRIL | PEVKVEGELG | GSVTIKCPLP | EMHVRIYLCR |
100:
EMAGSGTCGT | VVSTTNFIKA | EYKGRVTLKQ | YPRKNLFLVE | VTQLTESDSG |
150:
VYACGAGMNT | DRGKTQKVTL | NVHSEYEPSW | EEQPMPETPK | WFHLPYLFQM |
200:
PAYASSSKFV | TRVTTPAQRG | KVPPVHHSSP | TTQITHRPRV | SRASSVAGDK |
250:
PRTFLPSTTA | SKISALEGLL | KPQTPSYNHH | TRLHRQRALD | YGSQSGREGQ |
300:
GFHILIPTIL | GLFLLALLGL | VVKRAVERRK | ALSRRARRLA | VRMRALESSQ |
350:
RPRGSPRPRS | QNNIYSACPR | RARGADAAGT | GEAPVPGPGA | PLPPAPLQVS |
390:
ESPWLHAPSL | KTSCEYVSLY | HQPAAMMEDS | DSDDYINVPA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Human Fas apoptotic inhibitory molecule 3
ELISA Kit for Human Fas apoptotic inhibitory molecule 3
ELISA Kit for Human Fas apoptotic inhibitory molecule 3
CLIA Kit for Human Fas apoptotic inhibitory molecule 3
CLIA Kit for Human Fas apoptotic inhibitory molecule 3
CLIA Kit for Human Fas apoptotic inhibitory molecule 3
Polyclonal Antibody for Human Fas apoptotic inhibitory molecule 3
Polyclonal Antibody for Human Fas apoptotic inhibitory molecule 3
Polyclonal Antibody for Human Fas apoptotic inhibitory molecule 3
Monoclonal Antibody for Human Fas apoptotic inhibitory molecule 3
Monoclonal Antibody for Human Fas apoptotic inhibitory molecule 3
Monoclonal Antibody for Human Fas apoptotic inhibitory molecule 3
Protein for Human Fas apoptotic inhibitory molecule 3
Protein for Human Fas apoptotic inhibitory molecule 3
Protein for Human Fas apoptotic inhibitory molecule 3
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;INDUCTION
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Spleen .
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
B-cell .