Gene name:
Efemp1 (Fbln3) ;
Protein name:
EGF-containing fibulin-like extracellular matrix protein 1 ;
Alternative:
T16 protein ;Fibulin-3 (FIBL-3) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with ECM1 (By similarity). Interacts with TIMP3.
Function:
Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.
Subcellular Location:
Secreted
extracellular space
Secreted
extracellular space
extracellular matrix
Localizes to the lamina propria underneath the olfactory epithelium.
Protein Attributes:
50:
MLQTVFLTML | TLALVKSQVT | EETITYTQCT | DGYEWDPVRQ | QCKDIDECDI |
100:
VPDACKGGMK | CVNHYGGYLC | LPKTAQIIVN | NEQPQQETPA | AEASSGAATG |
150:
TIAARSMATS | GVIPGGGFIA | SATAVAGPEV | QTGRNNFVIR | RNPADPQRIP |
200:
SNPSHRIQCA | AGYEQSEHNV | CQDIDECTSG | THNCRLDQVC | INLRGSFTCH |
250:
CLPGYQKRGE | QCVDIDECSV | PPYCHQGCVN | TPGSFYCQCN | PGFQLAANNY |
300:
TCVDINECDA | SNQCAQQCYN | ILGSFICQCN | QGYELSSDRL | NCEDIDECRT |
350:
SSYLCQYQCV | NEPGKFSCMC | PQGYQVVRSR | TCQDINECET | TNECREDEMC |
400:
WNYHGGFRCY | PQNPCQDPYV | LTSENRCVCP | VSNTMCRDVP | QSIVYKYMNI |
450:
RSDRSVPSDI | FQIQATTIYA | NTINTFRIKS | GNENGEFYLR | QTSPVSAMLV |
493:
LVKSLTGPRE | HIVGLEMLTV | SSIGTFRTSS | VLRLTIIVGP | FSF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat EGF-containing fibulin-like extracellular matrix protein 1
ELISA Kit for Rat EGF-containing fibulin-like extracellular matrix protein 1
ELISA Kit for Rat EGF-containing fibulin-like extracellular matrix protein 1
CLIA Kit for Rat EGF-containing fibulin-like extracellular matrix protein 1
CLIA Kit for Rat EGF-containing fibulin-like extracellular matrix protein 1
CLIA Kit for Rat EGF-containing fibulin-like extracellular matrix protein 1
Polyclonal Antibody for Rat EGF-containing fibulin-like extracellular matrix protein 1
Polyclonal Antibody for Rat EGF-containing fibulin-like extracellular matrix protein 1
Polyclonal Antibody for Rat EGF-containing fibulin-like extracellular matrix protein 1
Monoclonal Antibody for Rat EGF-containing fibulin-like extracellular matrix protein 1
Monoclonal Antibody for Rat EGF-containing fibulin-like extracellular matrix protein 1
Monoclonal Antibody for Rat EGF-containing fibulin-like extracellular matrix protein 1
Protein for Rat EGF-containing fibulin-like extracellular matrix protein 1
Protein for Rat EGF-containing fibulin-like extracellular matrix protein 1
Protein for Rat EGF-containing fibulin-like extracellular matrix protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
tissue :
Lung .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION