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Index > Protein center > Fbxo45(Gene name) > Rat
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  • Fbxo45 (Gene name),
  • F-box/SPRY domain-containing protein 1 (Protein name ),  FBSP1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Fbxo45;
    Protein name:
    F-box/SPRY domain-containing protein 1;
    Alternative:
    F-box only protein 45;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Forms a complex with MYCBP2 and SKP1 but does not appear to form an authentic SCF (SKP1-CUL1-F-box protein) complex (By similarity). Interacts (via B30.2/SPRY domain) with TP73 (via SAM domain); leading to its ubiquination and degradation (By similarity). Interacts (via SRY domain) with UNC13A; leading to its degradation by the proteasome.
    Function:
    Component of E3 ubiquitin ligase complexes (By similarity). Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration (By similarity). Plays a role in the regulation of neurotransmission at mature neurons. May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway (By similarity). Specifically recognizes TP73, promoting its ubiquitination and degradation.
    Subcellular Location:
    Cell junction synapse postsynaptic cell membrane Cell junction synapse presynaptic cell membrane
    Protein Attributes:
    Sequence length:
    230
    Sequence:
    50:
    LASRALVCKH | WYRCLHGDEN | SEVWRSLCAR | SLEEAMRTDI | LCNLPSYKAK | 
    100:
    VRAFQHAFST | NDCSRNVYIK | KNGFTLHRNP | IAQSTDGART | KIGFSEGRHA | 
    150:
    WEVWWEGPLG | TVAVIGIATK | RAPMQCQGYV | ALLGSDDQSW | GWNLVDNNLL | 
    200:
    HNGEVNGSFP | QCNNAPKYQI | GERIRVILDM | EDKTLAFERG | YEFLGVAFRG | 
    230:
    LPKACLYPAV | SAVYGNTEVT | LVYLGKPLDG | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat F-box/SPRY domain-containing protein 1
    Cat.:
    E3813m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat F-box/SPRY domain-containing protein 1
    Cat.:
    E3813h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat F-box/SPRY domain-containing protein 1
    Cat.:
    E3813r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat F-box/SPRY domain-containing protein 1
    Cat.:
    U3813h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat F-box/SPRY domain-containing protein 1
    Cat.:
    U3813m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat F-box/SPRY domain-containing protein 1
    Cat.:
    U3813r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat F-box/SPRY domain-containing protein 1
    Cat.:
    P3813Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat F-box/SPRY domain-containing protein 1
    Cat.:
    P3813Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat F-box/SPRY domain-containing protein 1
    Cat.:
    P3813Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat F-box/SPRY domain-containing protein 1
    Monoclonal Antibody for Rat F-box/SPRY domain-containing protein 1
    Monoclonal Antibody for Rat F-box/SPRY domain-containing protein 1
    Protein for Rat F-box/SPRY domain-containing protein 1
    Protein for Rat F-box/SPRY domain-containing protein 1
    Protein for Rat F-box/SPRY domain-containing protein 1

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    Precision
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    Linearity
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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
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