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Index > Protein center > FCGR1B(Gene name) > Human
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  • FCGR1B (Gene name),
  • High affinity immunoglobulin gamma Fc receptor IB (Protein name ),  FCGRB_HUMAN from NCBI database.
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  • General Annotation
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    • Gene name:
    FCGR1B(IGFRB);
    Protein name:
    High affinity immunoglobulin gamma Fc receptor IB(IgG Fc receptor IB);
    Alternative:
    Fc-gamma RIB(FcRIB;hFcgammaRIB);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    280
    Sequence:
    50:
    MWFLTTLLLW | VPVDGQVDTT | KAVITLQPPW | VSVFQEETVT | LHCEVLHLPG | 
    100:
    SSSTQWFLNG | TATQTSTPSY | RITSASVNDS | GEYRCQRGLS | GRSDPIQLEI | 
    150:
    HRGWLLLQVS | SRVFMEGEPL | ALRCHAWKDK | LVYNVLYYRN | GKAFKFFHWN | 
    200:
    SNLTILKTNI | SHNGTYHCSG | MGKHRYTSAG | ISQYTVKGLQ | LPTPVWFHVL | 
    250:
    FYLAVGIMFL | VNTVLWVTIR | KELKRKKKWN | LEISLDSGHE | KKVISSLQED | 
    280:
    RHLEEELKCQ | EQKEEQLQEG | VHRKEPQGAT | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    STRING:
    9606.ENSP00000358391
    KEGG:
    hsa:2210
    MIM:
    601502
    Pfam:
    PF00047
    UniGene:
    Hs.534956
    String:
    Q92637
    SMR:
    Q92637
    Uniprot:
    Q92637
     
    FOR
    ELISA Kit for Human IgG Fc receptor IB
    CLIA Kit for Human IgG Fc receptor IB
    Polyclonal Antibody for Human IgG Fc receptor IB
    Monoclonal Antibody for Human IgG Fc receptor IB
    Protein for Human IgG Fc receptor IB

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Novel Fc gamma receptor I family gene products in human mononuclear cells."
      Porges A.J. , Redecha P.B. , Doebele R. , Pan L.C. , Salmon J.E. , Kimberly R.P.
      J. Clin. Invest.90:2102-2109(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 3);FUNCTION;SUBCELLULAR LOCATION;INDUCTION BY IFNG
      tissue: Blood.
    2. 2.
      "Definition of interferon gamma-response elements in a novel human Fc gamma receptor gene (Fc gamma RIb) and characterization of the gene structure."
      Benech P.D. , Sastry K.N. , Iyer R.R. , Eichbaum Q.G. , Raveh D.P. , Ezekowitz R.A.
      J. Exp. Med.176:1115-1123(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];INDUCTION BY IFNG
    3. 3.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The three genes of the human FCGR1 gene family encoding Fc gamma RI flank the centromere of chromosome 1 at 1p12 and 1q21."
      Maresco D.L. , Chang E. , Theil K.S. , Francke U. , Anderson C.L.
      Cytogenet. Cell Genet.73:157-163(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION
    5. 5.
      "Molecular characterization of six variant Fcgamma receptor class I (CD64) transcripts."
      Ernst L.K. , Duchemin A.-M. , Miller K.L. , Anderson C.L.
      Mol. Immunol.35:943-954(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;ALTERNATIVE SPLICING
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