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Index > Protein center > Fcgrt(Gene name) > Mouse
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  • Fcgrt (Gene name),
  • IgG receptor FcRn large subunit p51 (Protein name ),  FCGRN_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Fcgrt(Fcrn);
    Protein name:
    IgG receptor FcRn large subunit p51(FcRn);
    Alternative:
    Neonatal Fc receptor;IgG Fc fragment receptor transporter alpha chain;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    FcRn complex consist of two subunits: p51, and p14 which is equivalent to beta-2-microglobulin. It forms an MHC class I-like heterodimer.
    Function:
    Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the selective uptake of IgG from milk and helps newborn animals to acquire passive immunity. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    365
    Sequence:
    50:
    MGMPLPWALS | LLLVLLPQTW | GSETRPPLMY | HLTAVSNPST | GLPSFWATGW | 
    100:
    LGPQQYLTYN | SLRQEADPCG | AWMWENQVSW | YWEKETTDLK | SKEQLFLEAL | 
    150:
    KTLEKILNGT | YTLQGLLGCE | LASDNSSVPT | AVFALNGEEF | MKFNPRIGNW | 
    200:
    TGEWPETEIV | ANLWMKQPDA | ARKESEFLLN | SCPERLLGHL | ERGRRNLEWK | 
    250:
    EPPSMRLKAR | PGNSGSSVLT | CAAFSFYPPE | LKFRFLRNGL | ASGSGNCSTG | 
    300:
    PNGDGSFHAW | SLLEVKRGDE | HHYQCQVEHE | GLAQPLTVDL | DSSARSSVPV | 
    350:
    VGIVLGLLLV | VVAIAGGVLL | WGRMRSGLPA | PWLSLSGDDS | GDLLPGGNLP | 
    365:
    PEAEPQGANA | FPATS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    String:
    SMR:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse FcRn
    Cat.:
    E13790h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse FcRn
    Cat.:
    E13790r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse FcRn
    Cat.:
    E13790m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse FcRn
    Cat.:
    U13790h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse FcRn
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse FcRn
    Cat.:
    U13790m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse FcRn
    Polyclonal Antibody for Mouse FcRn
    Polyclonal Antibody for Mouse FcRn
    Monoclonal Antibody for Mouse FcRn
    Monoclonal Antibody for Mouse FcRn
    Monoclonal Antibody for Mouse FcRn
    Protein for Mouse FcRn
    Protein for Mouse FcRn
    Protein for Mouse FcRn

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    Precision
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    Linearity
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    References
    1. 1.
      "Structural and phylogenetic analysis of the MHC class I-like Fc receptor gene."
      Kandil E. , Noguchi M. , Ishibashi T. , Kasahara M.
      J. Immunol.154:5907-5918(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      strain: A/J.
      strain: AKR.
      strain: BALB/c.
      strain: C3H.
      strain: DBA/2.
      strain: P/J.
      strain: TW75.
      tissue: Small intestine.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: FVB/N.
      tissue: Small intestine.
    3. 3.
      Lubec G. , Sunyer B. , Chen W.-Q.
      Submitted (2009-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 167-173;IDENTIFICATION BY MASS SPECTROMETRY
      strain: OF1.
      tissue: Hippocampus.
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