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Index > Protein center > Fez1(Gene name) > Rat
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  • Fez1 (Gene name),
  • Fasciculation and elongation protein zeta-1 (Protein name ),  FEZ1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Fez1;
    Protein name:
    Fasciculation and elongation protein zeta-1;
    Alternative:
    Zygin-1;Zygin I;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer. Interacts with UBE4B, SAP30L, and with SCOC (By similarity). Interacts with the NH2-terminal variable region (V1) of PKC zeta and weakly with that of PKC epsilon.
    Function:
    May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. May participate in the transport of mitochondria and other cargos along microtubules.
    Subcellular Location:
    Cytoplasm cytoskeleton centrosome Cell membrane Co-localizes with both, alpha-and gamma-tubulin (By similarity). Translocated from the plasma membrane to the cytoplasm by activation of the PKC zeta.
    Protein Attributes:
    Sequence length:
    393
    Sequence:
    50:
    MEAPLVSLDE | EFEDIRPCCT | EDPEEKPQSL | YGTSPHHLED | PSLSELENFS | 
    100:
    SEIISFKSME | DLVNEFDEKL | NVCFRNYNAK | TENLAPVKNQ | LQIQEEEETL | 
    150:
    RDEEVWDALT | DNYIPSLSED | WRDPNIEALN | GNSSDTEIHE | KEEEDEFIEK | 
    200:
    SENDSGINEE | PLLTADQVIE | EIEEMMQNSP | DPEEEVEVLE | EEDGGEISSQ | 
    250:
    ADSVLLQEMQ | ALTQTFNNNW | SYEGLRHMSG | SELTELLDQV | EGAIRDFSEE | 
    300:
    LVHQLARRDE | LEFEKEVKNS | FITVLIEVQN | KQKEQRELMK | KRRKEKGLSL | 
    350:
    QSSRIEKGNQ | MPLKRFSMEG | ISNILQSGIR | QTFGSSGADR | QYLNTVIPYE | 
    393:
    KKSSPPSVED | LQMLTNILFA | MKEDNEKVPT | LLTDYILKVL | CPT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Fasciculation and elongation protein zeta-1
    ELISA Kit for Rat Fasciculation and elongation protein zeta-1
    ELISA Kit for Rat Fasciculation and elongation protein zeta-1
    CLIA Kit for Rat Fasciculation and elongation protein zeta-1
    CLIA Kit for Rat Fasciculation and elongation protein zeta-1
    CLIA Kit for Rat Fasciculation and elongation protein zeta-1
    Polyclonal Antibody for Rat Fasciculation and elongation protein zeta-1
    Polyclonal Antibody for Rat Fasciculation and elongation protein zeta-1
    Polyclonal Antibody for Rat Fasciculation and elongation protein zeta-1
    Monoclonal Antibody for Rat Fasciculation and elongation protein zeta-1
    Monoclonal Antibody for Rat Fasciculation and elongation protein zeta-1
    Monoclonal Antibody for Rat Fasciculation and elongation protein zeta-1
    Protein for Rat Fasciculation and elongation protein zeta-1
    Protein for Rat Fasciculation and elongation protein zeta-1
    Protein for Rat Fasciculation and elongation protein zeta-1

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    Precision
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    Linearity
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    References
    1. 1.
      "Mammalian homologue of the Caenorhabditis elegans UNC-76 protein involved in axonal outgrowth is a protein kinase C zeta-interacting protein."
      Kuroda S. , Nakagawa N. , Tokunaga C. , Tatematsu K. , Tanizawa K.
      J. Cell Biol.144:403-411(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PHOSPHORYLATION
      strain: Sprague-Dawley.
      tissue: Brain.
    2. 2.
      "Zigins: a family of synaptotagmin-interacting proteins related to unc-76."
      Sugita S. , von Poser C. , Rosahl T.W. , Hata Y. , Suedhof T.C.
      Submitted (1996-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    4. 4.
      "Fasciculation and elongation protein zeta-1 (FEZ1) participates in the polarization of hippocampal neuron by controlling the mitochondrial motility."
      Ikuta J. , Maturana A. , Fujita T. , Okajima T. , Tatematsu K. , Tanizawa K. , Kuroda S.
      Biochem. Biophys. Res. Commun.353:127-132(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      "Axonal guidance protein FEZ1 associates with tubulin and kinesin motor protein to transport mitochondria in neurites of NGF-stimulated PC12 cells."
      Fujita T. , Maturana A.D. , Ikuta J. , Hamada J. , Walchli S. , Suzuki T. , Sawa H. , Wooten M.W. , Okajima T. , Tatematsu K. , Tanizawa K. , Kuroda S.
      Biochem. Biophys. Res. Commun.361:605-610(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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