Ffar4 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comFfar4 ELISA Kit for Rat(Rattus norvegicus)

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Ffar4 (Gene name),

Free fatty acid receptor 4 (Protein name ), FFAR4_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Ffar4(Gpr120;O3far1);

Protein name:

Free fatty acid receptor 4;

Alternative:

Omega-3 fatty acid receptor 1;G-protein coupled receptor 120;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with ARRB2 following docosahexaenoic acid (DHA) stimulation.

Function:

Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.

Subcellular Location:

Cell membrane Multi-pass membrane protein Colocalized with ARRB2 following DHA treatment.

Protein Attributes:

Sequence length:

361

Sequence:

50:

100:

150:

200:

250:

300:

350:

361:

IRRNDLSVIS | T

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:294075

Pfam:

PF00001

UniGene:

Rn.82501

STRING:

10116.ENSRNOP00000032715

Uniprot:

Q2AC31

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ELISA Kit for Rat Free fatty acid receptor 4

Cat.:

E15282r

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96T

ELISA Kit for Rat Free fatty acid receptor 4

Cat.:

E15282h

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96T

ELISA Kit for Rat Free fatty acid receptor 4

Cat.:

E15282m

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96T

CLIA Kit for Rat Free fatty acid receptor 4

Cat.:

U15282m

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96T

CLIA Kit for Rat Free fatty acid receptor 4

Cat.:

U15282h

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Packing:

96T

CLIA Kit for Rat Free fatty acid receptor 4

Cat.:

U15282r

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Packing:

96T

Polyclonal Antibody for Rat Free fatty acid receptor 4

Cat.:

P15282Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat Free fatty acid receptor 4

Cat.:

P15282Rb-m

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40ug/0.2ml

Polyclonal Antibody for Rat Free fatty acid receptor 4

Cat.:

P15282Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Free fatty acid receptor 4

Protein for Rat Free fatty acid receptor 4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and characterization of rat GPR120."
Yano T. , Katsuma S. , Hirasawa A. , Tsujimoto G.
Submitted (2005-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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