Fgf1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comFgf1 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Fgf1(Gene name) > Rat

Fgf1 (Gene name),

Heparin-binding growth factor 1 (Protein name ), FGF1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Fgf1(Fgf-1;Fgfa);

Protein name:

Heparin-binding growth factor 1(HBGF-1);

Alternative:

Heparin-binding growth factor 1(HBGF-1);Acidic fibroblast growth factor(aFGF);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Found in a complex with FGFBP1, FGF1 and FGF2. Interacts with FGFBP1. Part of a Cu(2+)-dependent multiprotein aggregate containing FGF1, S100A13 and SYT1. Interacts with SYT1. Interacts with S100A13.

Function:

Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.

Subcellular Location:

Secreted Cytoplasm Cytoplasm cell cortex Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1.

Protein Attributes:

Sequence length:

155

Sequence:

50:

100:

150:

155:

PVSSD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:25317

SMR:

P61149

UniGene:

Rn.88013

Pfam:

PF00167

String:

P61149

Uniprot:

P61149

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ELISA Kit for Rat HBGF-1

Cat.:

E0032h

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96T

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ELISA Kit for Rat HBGF-1

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E0032m

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96T

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ELISA Kit for Rat HBGF-1

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E0032r

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ELISA Kit for Rat HBGF-1

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E0032p

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ELISA Kit for Rat HBGF-1

Cat.:

E0032b

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ELISA Kit for Rat HBGF-1

Cat.:

E0032d

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ELISA Kit for Rat HBGF-1

Cat.:

E0032c

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CLIA Kit for Rat HBGF-1

Cat.:

U0032r

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96T

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CLIA Kit for Rat HBGF-1

Cat.:

U0032p

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96T

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CLIA Kit for Rat HBGF-1

Cat.:

U0032m

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Looking for manual.

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96T

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CLIA Kit for Rat HBGF-1

Cat.:

U0032h

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96T

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CLIA Kit for Rat HBGF-1

Cat.:

U0032d

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96T

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CLIA Kit for Rat HBGF-1

Cat.:

U0032b

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96T

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CLIA Kit for Rat HBGF-1

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U0032c

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Polyclonal Antibody for Rat HBGF-1

Cat.:

P0032Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat HBGF-1

Cat.:

P0032Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat HBGF-1

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P0032Rb-m

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40ug/0.2ml

Polyclonal Antibody for Rat HBGF-1

Monoclonal Antibody for Rat HBGF-1

Protein for Rat HBGF-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤4.7%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤6.8%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

Recovery was determined by spiking various levels of FGF1 into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	95	93-97
Plasma	97	96-102

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of FGF1 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	92-100%	97-104%	95-98%	91-96%
EDTA plasma(n=5)	89-93%	102-105%	94-97%	93-98%
heparin plasma(n=5)	91-95%	96-99%	106-108%	87-93%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The nucleotide sequence of rat heparin binding growth factor 1 (HBGF-1)."
Goodrich S. , Yan G.C. , Bahrenburg K. , Mansson P.E.
Nucleic Acids Res.17:2867-2867(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Astrocytes produce and secrete FGF-1, which promotes the production of apoE-HDL in a manner of autocrine action."
Ito J. , Nagayasu Y. , Lu R. , Kheirollah A. , Hayashi M. , Yokoyama S.
J. Lipid Res.46:679-686(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
3.

"Structure of rat acidic fibroblast growth factor at 1.4 A resolution."
Kulahin N. , Kiselyov V. , Kochoyan A. , Kristensen O. , Kastrup J.S. , Berezin V. , Bock E. , Gajhede M.
Acta Crystallogr. F63:65-68(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.4 ANGSTROMS) OF 22-155
4.

"Dimerization effect of sucrose octasulfate on rat FGF1."
Kulahin N. , Kiselyov V. , Kochoyan A. , Kristensen O. , Kastrup J.S. , Berezin V. , Bock E. , Gajhede M.
Acta Crystallogr. F64:448-452(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 22-153

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