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Index > Protein center > Fgf23(Gene name) > Mouse
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  • Fgf23 (Gene name),
  • Fibroblast growth factor 23 (Protein name ),  FGF23_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Fgf23;
    Protein name:
    Fibroblast growth factor 23(FGF-23);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL and heparan sulfate glycosaminoglycans that function as coreceptors.
    Function:
    Regulator of phosphate homeostasis (By similarity). Inhibits renal tubular phosphate transport by reducing SLC34A1 levels (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism (By similarity). Negatively regulates osteoblasts differentiation and matrix mineralization (By similarity). Upregulates EGR1 expression in the presence of KL.
    Subcellular Location:
    Secreted Secretion is dependent on O-glycosylation.
    Protein Attributes:
    Sequence length:
    251
    Sequence:
    50:
    MLGTCLRLLV | GVLCTVCSLG | TARAYPDTSP | LLGSNWGSLT | HLYTATARTS | 
    100:
    YHLQIHRDGH | VDGTPHQTIY | SALMITSEDA | GSVVITGAMT | RRFLCMDLHG | 
    150:
    NIFGSLHFSP | ENCKFRQWTL | ENGYDVYLSQ | KHHYLVSLGR | AKRIFQPGTN | 
    200:
    PPPFSQFLAR | RNEVPLLHFY | TVRPRRHTRS | AEDPPERDPL | NVLKPRPRAT | 
    250:
    PVPVSCSREL | PSAEEGGPAA | SDPLGVLRRG | RGDARGGAGG | ADRCRPFPRF | 
    251:
    V
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse FGF-23
    Cat.:
    E0746m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse FGF-23
    Cat.:
    E0746h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse FGF-23
    Cat.:
    E0746r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse FGF-23
    Cat.:
    U0746h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse FGF-23
    Cat.:
    U0746m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse FGF-23
    Cat.:
    U0746r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse FGF-23
    Cat.:
    P0746Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse FGF-23
    Cat.:
    P0746Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse FGF-23
    Cat.:
    P0746Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse FGF-23
    Monoclonal Antibody for Mouse FGF-23
    Monoclonal Antibody for Mouse FGF-23
    Protein for Mouse FGF-23
    Protein for Mouse FGF-23
    Protein for Mouse FGF-23

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    References
    1. 1.
      "Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain."
      Yamashita T. , Yoshioka M. , Itoh N.
      Biochem. Biophys. Res. Commun.277:494-498(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23."
      White K.E. , Evans W.E. , O'Riordan J.L.H. , Speer M.C. , Econs M.J. , Lorenz-Depiereux B. , Grabowski M. , Meitinger T. , Strom T.M.
      Nat. Genet.26:345-348(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BALB/c.
      tissue: Embryo.
    3. 3.
      "Klotho converts canonical FGF receptor into a specific receptor for FGF23."
      Urakawa I. , Yamazaki Y. , Shimada T. , Iijima K. , Hasegawa H. , Okawa K. , Fujita T. , Fukumoto S. , Yamashita T.
      Nature444:770-774(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH KL AND FGFR1
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