Protein name:
Fibroblast growth factor 23 (FGF-23) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL and heparan sulfate glycosaminoglycans that function as coreceptors.
Function:
Regulator of phosphate homeostasis (By similarity). Inhibits renal tubular phosphate transport by reducing SLC34A1 levels (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism (By similarity). Negatively regulates osteoblasts differentiation and matrix mineralization (By similarity). Upregulates EGR1 expression in the presence of KL.
Subcellular Location:
Secreted
Secretion is dependent on O-glycosylation.
Protein Attributes:
50:
MLGTCLRLLV | GVLCTVCSLG | TARAYPDTSP | LLGSNWGSLT | HLYTATARTS |
100:
YHLQIHRDGH | VDGTPHQTIY | SALMITSEDA | GSVVITGAMT | RRFLCMDLHG |
150:
NIFGSLHFSP | ENCKFRQWTL | ENGYDVYLSQ | KHHYLVSLGR | AKRIFQPGTN |
200:
PPPFSQFLAR | RNEVPLLHFY | TVRPRRHTRS | AEDPPERDPL | NVLKPRPRAT |
250:
PVPVSCSREL | PSAEEGGPAA | SDPLGVLRRG | RGDARGGAGG | ADRCRPFPRF |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Mouse FGF-23
ELISA Kit for Mouse FGF-23
ELISA Kit for Mouse FGF-23
CLIA Kit for Mouse FGF-23
CLIA Kit for Mouse FGF-23
CLIA Kit for Mouse FGF-23
Polyclonal Antibody for Mouse FGF-23
Polyclonal Antibody for Mouse FGF-23
Polyclonal Antibody for Mouse FGF-23
Monoclonal Antibody for Mouse FGF-23
Monoclonal Antibody for Mouse FGF-23
Monoclonal Antibody for Mouse FGF-23
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
BALB/c .
tissue :
Embryo .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH KL AND FGFR1