FICD ELISA Kit for Human(Homo sapiens) | EIAab.comFICD ELISA Kit for Human(Homo sapiens) | EIAab.com

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FICD (Gene name),

Adenosine monophosphate-protein transferase FICD (Protein name ), FICD_HUMAN from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

FICD(UNQ3041/PRO9857;HIP13;HYPE);

Protein name:

Adenosine monophosphate-protein transferase FICD;

Alternative:

FIC domain-containing protein;AMPylator FICD;Huntingtin-interacting protein 13(HIP-13);Huntingtin yeast partner E;Huntingtin-interacting protein E;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with HD.

Function:

Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified.

Subcellular Location:

Membrane Single-pass membrane protein

Protein Attributes:

Sequence length:

458

Sequence:

50:

MMLIPMASVM | AVTEPKWVSV | WSRFLWVTLL | SMVLGSLLAL | LLPLGAVEEQ |

100:

CLAVLKGLYL | LRSKPDRAQH | AATKCTSPST | ELSITSRGAT | LLVAKTKASP |

150:

AGKLEARAAL | NQALEMKRQG | KREKAQKLFM | HALKMDPDFV | DALTEFGIFS |

200:

EEDKDIIQAD | YLYTRALTIS | PYHEKALVNR | DRTLPLVEEI | DQRYFSIIDS |

250:

KVKKVMSIPK | GNSALRRVME | ETYYHHIYHT | VAIEGNTLTL | SEIRHILETR |

300:

YAVPGKSLEE | QNEVIGMHAA | MKYINTTLVS | RIGSVTISDV | LEIHRRVLGY |

350:

VDPVEAGRFR | TTQVLVGHHI | PPHPQDVEKQ | MQEFVQWLNS | EEAMNLHPVE |

400:

FAALAHYKLV | YIHPFIDGNG | RTSRLLMNLI | LMQAGYPPIT | IRKEQRSDYY |

450:

HVLEAANEGD | VRPFIRFIAK | CTETTLDTLL | FATTEYSVAL | PEAQPNHSGF |

458:

KETLPVKP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

KEGG:

UniGene:

String:

Pfam:

STRING:

9606.ENSP00000354421

Uniprot:

FOR

ELISA Kit for Human Adenosine monophosphate-protein transferase FICD

ELISA Kit for Human Adenosine monophosphate-protein transferase FICD

ELISA Kit for Human Adenosine monophosphate-protein transferase FICD

CLIA Kit for Human Adenosine monophosphate-protein transferase FICD

CLIA Kit for Human Adenosine monophosphate-protein transferase FICD

CLIA Kit for Human Adenosine monophosphate-protein transferase FICD

Polyclonal Antibody for Human Adenosine monophosphate-protein transferase FICD

Polyclonal Antibody for Human Adenosine monophosphate-protein transferase FICD

Polyclonal Antibody for Human Adenosine monophosphate-protein transferase FICD

Monoclonal Antibody for Human Adenosine monophosphate-protein transferase FICD

Monoclonal Antibody for Human Adenosine monophosphate-protein transferase FICD

Monoclonal Antibody for Human Adenosine monophosphate-protein transferase FICD

Protein for Human Adenosine monophosphate-protein transferase FICD

Protein for Human Adenosine monophosphate-protein transferase FICD

Protein for Human Adenosine monophosphate-protein transferase FICD

R&D Technical Data

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Precision

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Recovery

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Linearity

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References

1.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
2.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Cervix.
4.

"Huntingtin interacts with a family of WW domain proteins."
Faber P.W. , Barnes G.T. , Srinidhi J. , Chen J. , Gusella J.F. , MacDonald M.E.
Hum. Mol. Genet.7:1463-1474(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 275-458;INTERACTION WITH HD
tissue: Frontal cortex.
5.

"The fic domain: regulation of cell signaling by adenylylation."
Worby C.A. , Mattoo S. , Kruger R.P. , Corbeil L.B. , Koller A. , Mendez J.C. , Zekarias B. , Lazar C. , Dixon J.E.
Mol. Cell34:93-103(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;TISSUE SPECIFICITY;MUTAGENESIS OF HIS-363
6.

"Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins."
Engel P. , Goepfert A. , Stanger F.V. , Harms A. , Schmidt A. , Schirmer T. , Dehio C.
Nature482:107-110(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;ENZYME REGULATION;MUTAGENESIS OF GLU-234

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