Protein name:
Pre-mRNA 3'-end-processing factor FIP1 ;
Alternative:
FIP1-like 1 protein ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Component of the cleavage and polyadenylation specificity factor (CPSF) complex, composed of CPSF1, CPSF2, CPSF3, CPSF4 and FIP1L1. Found in a complex with CPSF1, FIP1L1 and PAPOLA. Interacts with CPSF1, CPSF4, CSTF2, CSTF3 and PAPOLA.
Function:
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MSAGEVERLV | ELSGGTGGDE | EEEWLYGGPW | DVHVHSDLAK | DLDENEVERP |
100:
EEENASANPP | SGIEEEAAEN | GVAKPKVTET | EDDSDSDSDD | DEDDVHVTIG |
150:
DIKTGAPQYG | SYGTAPVNLN | IKAGGRVYGN | TGTKVKGVDL | DAPGSINGVP |
200:
LLEVDLDSFE | DKPWRKPGAD | LSDYFNYGFN | EDTWKAYCEK | QKRIRMGLEV |
250:
IPVTSTTNKI | TVQQGRTGNS | EKEAALPSTK | AEFTSPPSLF | KTGLPPSRNS |
300:
TSSQSQTSTA | SRKASSSVGK | WQDRYGRAES | PDLRRLPGAI | DVIGQTITIS |
350:
RVEGRRRANE | NSNIQVLSDR | SATEVDNNFS | KPPPFFPPGA | PPTHLPPPPF |
400:
LPPPPTVSTA | PPLIPPPGIP | ITVPPPGFPP | PPGAPPPSLI | PTIESGHSSG |
450:
YDSRSARAFP | YGNVAFPHLT | SSAPSWPSLV | DTTKQWDYYA | RREKDRDRDR |
500:
ERDRDRERER | DRDRERERTR | ERERERDHSP | TPSVFNSDEE | RYRYREYAER |
550:
GYERHRASRE | KEERHRERRH | REKEETRHKS | SRSNSRRRHE | SEEGDSHRRH |
581:
KHKKSKRSKE | GKEAGSEPVP | EQESTEAAPA | E
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Mouse Pre-mRNA 3'-end-processing factor FIP1
ELISA Kit for Mouse Pre-mRNA 3'-end-processing factor FIP1
ELISA Kit for Mouse Pre-mRNA 3'-end-processing factor FIP1
CLIA Kit for Mouse Pre-mRNA 3'-end-processing factor FIP1
CLIA Kit for Mouse Pre-mRNA 3'-end-processing factor FIP1
CLIA Kit for Mouse Pre-mRNA 3'-end-processing factor FIP1
Polyclonal Antibody for Mouse Pre-mRNA 3'-end-processing factor FIP1
Polyclonal Antibody for Mouse Pre-mRNA 3'-end-processing factor FIP1
Polyclonal Antibody for Mouse Pre-mRNA 3'-end-processing factor FIP1
Monoclonal Antibody for Mouse Pre-mRNA 3'-end-processing factor FIP1
Monoclonal Antibody for Mouse Pre-mRNA 3'-end-processing factor FIP1
Monoclonal Antibody for Mouse Pre-mRNA 3'-end-processing factor FIP1
Protein for Mouse Pre-mRNA 3'-end-processing factor FIP1
Protein for Mouse Pre-mRNA 3'-end-processing factor FIP1
Protein for Mouse Pre-mRNA 3'-end-processing factor FIP1
R&D Technical Data
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Precision
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Recovery
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Linearity
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-558 (ISOFORM 3)
strain :
C57BL/6J .
tissue :
Embryonic spinal cord .
tissue :
Liver .
tissue :
Small intestine .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
strain :
FVB/N .
tissue :
Mammary gland .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-479; THR-481; SER-483 AND SER-487;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-280 AND SER-479;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]