FKBP4 ELISA Kit for Bovine(Bos taurus) | EIAab.comFKBP4 ELISA Kit for Bovine(Bos taurus)

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FKBP4 (Gene name),

Peptidyl-prolyl cis-trans isomerase FKBP4 (Protein name ), FKBP4_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

FKBP4;

Protein name:

Peptidyl-prolyl cis-trans isomerase FKBP4(PPIase FKBP4);

Alternative:

FK506-binding protein 4(FKBP-4);52 kDa FK506-binding protein(52 kDa FKBP;FKBP-52);Immunophilin FKBP52;HSP-binding immunophilin(HBI);Rotamase;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Homodimer (By similarity). Associates with HSP90 and HSP70 in unactivated steroid hormone receptor complexes. Also interacts with peroxisomal phytanoyl-CoA alpha-hydroxylase (PHYH). Interacts with NR3C1 and dynein (By similarity). Interacts with HSF1 in the HSP90 complex (By similarity). Associates with tubulin (By similarity). Interacts with MAPT/TAU (By similarity). Interacts (via TPR domain) with S100A1, S100A2 and S100A6; the interaction is Ca(2+) dependent (By similarity). Interaction with S100A1 and S100A2 (but not with S100A6) leads to inhibition of FKBP4-HSP90 interaction.

Function:

Immunophilin protein with PPIase and co-chaperone activities (By similarity). Component of unliganded steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) (By similarity). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments (By similarity). The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening (By similarity). Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly.

Subcellular Location:

Cytoplasm cytosol Nucleus Cytoplasm cytoskeleton

Protein Attributes:

Sequence length:

459

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

459:

GQPQVEAEA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q9TRY0

Pfam:

PF00254

UniGene:

Bt.4797

KEGG:

bta:508535

String:

Q9TRY0

Uniprot:

Q9TRY0

FOR

ELISA Kit for Bovine PPIase FKBP4

Cat.:

E11170h

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Manual:

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Packing:

96T

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ELISA Kit for Bovine PPIase FKBP4

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ELISA Kit for Bovine PPIase FKBP4

Cat.:

E11170m

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Packing:

96T

ELISA Kit for Bovine PPIase FKBP4

Cat.:

E11170r

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Packing:

96T

ELISA Kit for Bovine PPIase FKBP4

Cat.:

E11170b

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Packing:

96T

CLIA Kit for Bovine PPIase FKBP4

Cat.:

U11170r

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MSDS:

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Packing:

96T

CLIA Kit for Bovine PPIase FKBP4

Cat.:

U11170m

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine PPIase FKBP4

MSDS:

Please sign in first.

CLIA Kit for Bovine PPIase FKBP4

Cat.:

U11170b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Bovine PPIase FKBP4

Cat.:

U11170h

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Manual:

Looking for manual.

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96T

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Polyclonal Antibody for Bovine PPIase FKBP4

Cat.:

P11170Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine PPIase FKBP4

Cat.:

P11170Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine PPIase FKBP4

Cat.:

P11170Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Bovine PPIase FKBP4

Protein for Bovine PPIase FKBP4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Characterization of 954 bovine full-CDS cDNA sequences."
Harhay G.P. , Sonstegard T.S. , Keele J.W. , Heaton M.P. , Clawson M.L. , Snelling W.M. , Wiedmann R.T. , Van Tassell C.P. , Smith T.P.L.
BMC Genomics6:166-166(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
2.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2005-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Crossbred X Angus.
tissue: Ileum.
3.

"Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes."
Peattie D.A. , Harding M.W. , Fleming M.A. , Decenzo M.T. , Lippke J.A. , Livingston D.J. , Benasutti M.
Proc. Natl. Acad. Sci. U.S.A.89:10974-10978(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-28; 75-83; 89-98; 122-137; 164-175; 214-222; 245-250; 277-282; 345-354; 410-424 AND 427-440
tissue: Thymus.
4.

"The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13."
Yem A.W. , Tomasselli A.G. , Heinrikson R.L. , Zurcher-Neely H. , Ruff V.A. , Johnson R.A. , Deibel M.R. Jr.
J. Biol. Chem.267:2868-2871(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-18 AND 121-137
tissue: Thymus.

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