Fkbp8 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comFkbp8 ELISA Kit for Rat(Rattus norvegicus)

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Fkbp8 (Gene name),

Peptidyl-prolyl cis-trans isomerase FKBP8 (Protein name ), FKBP8_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Fkbp8;

Protein name:

Peptidyl-prolyl cis-trans isomerase FKBP8(PPIase FKBP8);

Alternative:

Rotamase;FK506-binding protein 8(FKBP-8);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homomultimers or heteromultimers (Potential). Forms heterodimer with calmodulin. When activated by calmodulin and calcium, interacts with the BH4 domain of BCL2 and weakly with BCLX isoform Bcl-X(L). Does not bind and inhibit calcineurin. Interacts with ZFYVE27; may negatively regulate ZFYVE27 phosphorylation.

Function:

Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.

Subcellular Location:

Mitochondrion membrane Single-pass membrane protein Cytoplasmic side

Protein Attributes:

Sequence length:

403

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

403:

ARN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00254

SMR:

Q3B7U9

String:

Q3B7U9

KEGG:

rno:290652

UniGene:

Rn.99789

STRING:

10116.ENSRNOP00000027040

Uniprot:

Q3B7U9

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ELISA Kit for Rat PPIase FKBP8

Cat.:

E11198h

Price:

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Manual:

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Packing:

96T

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ELISA Kit for Rat PPIase FKBP8

Cat.:

E11198m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Rat PPIase FKBP8

Cat.:

E11198r

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MSDS:

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Packing:

96T

CLIA Kit for Rat PPIase FKBP8

Cat.:

U11198h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Rat PPIase FKBP8

Cat.:

U11198m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat PPIase FKBP8

Cat.:

U11198r

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat PPIase FKBP8

Cat.:

P11198Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat PPIase FKBP8

Monoclonal Antibody for Rat PPIase FKBP8

Protein for Rat PPIase FKBP8

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Spleen.

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