Gene name:
FLVCR1 (FLVCR) ;
Protein name:
Feline leukemia virus subgroup C receptor-related protein 1 (Feline leukemia virus subgroup C receptor;hFLVCR) ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with HPX.
Function:
Heme transporter that exports cytoplasmic heme. It can also export coproporphyrin and protoporphyrin IX, which are both intermediate products in the heme biosynthetic pathway. Does not export bilirubin. Heme export depends on the presence of HPX and may be required to protect developing erythroid cells from heme toxicity. Heme export also provides protection from heme or ferrous iron toxicities in liver and brain. Causes susceptibility to FeLV-C in vitro.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MARPDDEEGA | AVAPGHPLAK | GYLPLPRGAP | VGKESVELQN | GPKAGTFPVN |
100:
GAPRDSLAAA | SGVLGGPQTP | LAPEEETQAR | LLPAGAGAET | PGAESSPLPL |
150:
TALSPRRFVV | LLIFSLYSLV | NAFQWIQYSI | ISNVFEGFYG | VTLLHIDWLS |
200:
MVYMLAYVPL | IFPATWLLDT | RGLRLTALLG | SGLNCLGAWI | KCGSVQQHLF |
250:
WVTMLGQCLC | SVAQVFILGL | PSRIASVWFG | PKEVSTACAT | AVLGNQLGTA |
300:
VGFLLPPVLV | PNTQNDTNLL | ACNISTMFYG | TSAVATLLFI | LTAIAFKEKP |
350:
RYPPSQAQAA | LQDSPPEEYS | YKKSIRNLFK | NIPFVLLLIT | YGIMTGAFYS |
400:
VSTLLNQMIL | TYYEGEEVNA | GRIGLTLVVA | GMVGSILCGL | WLDYTKTYKQ |
450:
TTLIVYILSF | IGMVIFTFTL | DLRYIIIVFV | TGGVLGFFMT | GYLPLGFEFA |
500:
VEITYPESEG | TSSGLLNASA | QIFGILFTLA | QGKLTSDYGP | KAGNIFLCVW |
550:
MFIGIILTAL | IKSDLRRHNI | NIGITNVDVK | AIPADSPTDQ | EPKTVMLSKQ |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human Feline leukemia virus subgroup C receptor
ELISA Kit for Human Feline leukemia virus subgroup C receptor
CLIA Kit for Human Feline leukemia virus subgroup C receptor
CLIA Kit for Human Feline leukemia virus subgroup C receptor
Polyclonal Antibody for Human Feline leukemia virus subgroup C receptor
Polyclonal Antibody for Human Feline leukemia virus subgroup C receptor
Monoclonal Antibody for Human Feline leukemia virus subgroup C receptor
Monoclonal Antibody for Human Feline leukemia virus subgroup C receptor
Protein for Human Feline leukemia virus subgroup C receptor
Protein for Human Feline leukemia virus subgroup C receptor
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;CHARACTERIZATION OF FELV-C RECEPTOR FUNCTION
tissue :
Lymphocyte .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANTS PRO-52 AND MET-544
tissue :
Duodenum .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GENE STRUCTURE
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;DEVELOPMENTAL STAGE
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TOPOLOGY;GLYCOSYLATION
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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tissue :
Leukemic T-cell .
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Cervix carcinoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ALTERNATIVE SPLICING (ISOFORM 2);FUNCTION (ISOFORM 2);SUBCELLULAR LOCATION (ISOFORM 2)
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS PCARP ASP-121; ARG-192 AND THR-241
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT PCARP ARG-493