Protein name:
Far upstream element-binding protein 2 (FUSE-binding protein 2) ;
Alternative:
MAP2 RNA trans-acting protein 1 (MARTA1) ;KH type-splicing regulatory protein (KSRP) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Part of a ternary complex containing FUBP2, PTBP1, PTBP2 and HNRPH1. Interacts with PARN.
Function:
Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs (By similarity). Binds to the dendritic targeting element and may play a role in mRNA trafficking.
Subcellular Location:
Nucleus
Cytoplasm
A small proportion is also found in the cytoplasm of neuronal cell bodies and dendrites.
Protein Attributes:
50:
MSDYSTGGPP | PGPPPPAGGG | GGAAGAGGGP | PPGPPGAGDR | GGGGPGGGGP |
100:
GGGGASGGPS | QPPGGGGPGI | RKDAFADAVQ | RARQIAAKIG | GDAATTVNNN |
150:
TPDFGFGGQK | RQLEDGDQPD | SKKLASQGDS | IGSQLGPIHP | PPRTSMTEEY |
200:
RVPDGMVGLI | IGRGGEQINK | IQQDSGCKVQ | ISPDSGGLPE | RSVSLTGAPE |
250:
SVQKAKMMLD | DIVSRGRGGP | PGQFHDNANG | GQNGTVQEIM | IPAGKAGLVI |
300:
GKGGETIKQL | QERAGVKMIL | IQDGSQNTNV | DKPLRIIGDP | YKVQQACEMV |
350:
MDILRERDQG | GFGDRNEYGS | RVGGGIDVPV | PRHSVGVVIG | RSGEMIKKIQ |
400:
NDAGVRIQFK | QDDGTGPEKI | AHIMGPPDRC | EHAARIINDL | LQSLRSGPPG |
450:
PPGAPGMPPG | GRGRGRGQGN | WGPPGGEMTF | SIPTHKCGLV | IGRGGENVKA |
500:
INQQTGAFVE | ISRQLPPNGD | PNFKLFVIRG | SPQQIDHAKQ | LIEEKIEGPL |
550:
CPVGPGPGGP | GPAGPMGPFH | PGPFNQGPPG | APPHAGGPPP | HQYPPQGWGN |
600:
TYPEWQPPAP | HDPNKAAAAA | TDPNAAWAAY | YSHYYQQPPG | PVPGPAPAPA |
650:
APPAQGEPPQ | PPPTGQSDYT | KAWEEYYKKI | GQQPQQPGAP | PQQDYTKAWE |
700:
EYYKKQAQVA | TGGGPGAPPG | SQPDYSAAWA | EYYRQQAAYY | GQTPGPGGPQ |
721:
PPSTQQGQQQ | ATEANGYELH | L
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Chicken
ELISA Kit for Rat FUSE-binding protein 2
ELISA Kit for Rat FUSE-binding protein 2
ELISA Kit for Rat FUSE-binding protein 2
ELISA Kit for Rat FUSE-binding protein 2
CLIA Kit for Rat FUSE-binding protein 2
CLIA Kit for Rat FUSE-binding protein 2
CLIA Kit for Rat FUSE-binding protein 2
CLIA Kit for Rat FUSE-binding protein 2
Polyclonal Antibody for Rat FUSE-binding protein 2
Polyclonal Antibody for Rat FUSE-binding protein 2
Polyclonal Antibody for Rat FUSE-binding protein 2
Polyclonal Antibody for Rat FUSE-binding protein 2
Monoclonal Antibody for Rat FUSE-binding protein 2
Monoclonal Antibody for Rat FUSE-binding protein 2
Monoclonal Antibody for Rat FUSE-binding protein 2
Monoclonal Antibody for Rat FUSE-binding protein 2
Protein for Rat FUSE-binding protein 2
Protein for Rat FUSE-binding protein 2
Protein for Rat FUSE-binding protein 2
Protein for Rat FUSE-binding protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 73-87; 89-108 AND 475-486;SUBCELLULAR LOCATION;FUNCTION
tissue :
Brain .