Gas2 ELISA Kit for Mouse(Mus musculus) | EIAab.comGas2 ELISA Kit for Mouse(Mus musculus)

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Gas2 (Gene name),

Growth arrest-specific protein 2 (Protein name ), GAS2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Gas2(Gas-2);

Protein name:

Growth arrest-specific protein 2(GAS-2);

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May play a role in chondrocyte proliferation and differentiation, and in limb myogenesis. May be involved in the regulation of the apoptosis in the interdigital tissues of the developing hindlimb. May be involved in the membrane ruffling process.

Subcellular Location:

Cytoplasm cytoskeleton Membrane Peripheral membrane protein Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles.

Protein Attributes:

Sequence length:

314

Sequence:

50:

100:

150:

200:

250:

300:

314:

LVVSATYKAK | KEIK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.207360

Pfam:

PF00307

STRING:

10090.ENSMUSP00000103217

SMR:

P11862

KEGG:

mmu:14453

String:

P11862

Uniprot:

P11862

FOR

ELISA Kit for Mouse GAS-2

CLIA Kit for Mouse GAS-2

Polyclonal Antibody for Mouse GAS-2

Monoclonal Antibody for Mouse GAS-2

Protein for Mouse GAS-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Genes specifically expressed at growth arrest of mammalian cells."
Schneider C. , King R.M. , Philipson L.
Cell54:787-793(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Embryo.
tissue: Kidney.
3.

"Gas2, a growth arrest-specific protein, is a component of the microfilament network system."
Brancolini C. , Bottega S. , Schneider C.
J. Cell Biol.117:1251-1261(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
4.

"Phosphorylation of the growth arrest-specific protein Gas2 is coupled to actin rearrangements during Go-->G1 transition in NIH 3T3 cells."
Brancolini C. , Schneider C.
J. Cell Biol.124:743-756(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;SUBCELLULAR LOCATION
5.

"Microfilament reorganization during apoptosis: the role of Gas2, a possible substrate for ICE-like proteases."
Brancolini C. , Benedetti M. , Schneider C.
EMBO J.14:5179-5190(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING
6.

"gas2 is a multifunctional gene involved in the regulation of apoptosis and chondrogenesis in the developing mouse limb."
Lee K.K. , Tang M.K. , Yew D.T. , Chow P.H. , Yee S.P. , Schneider C. , Brancolini C.
Dev. Biol.207:14-25(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DEVELOPMENTAL STAGE
7.

"Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
Zhou H. , Ye M. , Dong J. , Han G. , Jiang X. , Wu R. , Zou H.
J. Proteome Res.7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
8.

"Solution structure of the GAS2 domain of the growth arrest specific 2 protein."
RIKEN structural genomics initiative (RSGI)
Submitted (2005-01) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 198-284

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