Gabra1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comGabra1 ELISA Kit for Rat(Rattus norvegicus)

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Gabra1 (Gene name),

Gamma-aminobutyric acid receptor subunit alpha-1 (Protein name ), GBRA1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Gabra1(Gabra-1);

Protein name:

Gamma-aminobutyric acid receptor subunit alpha-1;

Alternative:

GABA(A) receptor subunit alpha-1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Binds UBQLN1. Interacts with TRAK1.

Function:

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

Subcellular Location:

Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

455

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

455:

PTPHQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:29705

Pfam:

PF02931

UniGene:

Rn.28463

String:

P62813

SMR:

P62813

STRING:

10116.ENSRNOP00000004725

Uniprot:

P62813

FOR

ELISA Kit for Rat Gamma-aminobutyric acid receptor subunit alpha-1

CLIA Kit for Rat Gamma-aminobutyric acid receptor subunit alpha-1

Polyclonal Antibody for Rat Gamma-aminobutyric acid receptor subunit alpha-1

Monoclonal Antibody for Rat Gamma-aminobutyric acid receptor subunit alpha-1

Protein for Rat Gamma-aminobutyric acid receptor subunit alpha-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and expression of a novel rat GABAA receptor."
Lolait S.J. , O'Carroll A.-M. , Kusano K. , Muller J.-M. , Brownstein M.J. , Mahan L.C.
FEBS Lett.246:145-148(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];FUNCTION;SUBCELLULAR LOCATION;SUBUNIT
2.

"A novel alpha subunit in rat brain GABAA receptors."
Khrestchatisky M. , Maclennan A.J. , Chiang M.Y. , Xu W. , Jackson M.B. , Brecha N. , Sternini C. , Olsen R.W. , Tobin A.J.
Neuron3:745-753(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"GABAA-receptor expressed from rat brain alpha- and beta-subunit cDNAs displays potentiation by benzodiazepine receptor ligands."
Malherbe P. , Draguhn A. , Multhaup G. , Beyreuther K. , Mohler H.
Brain Res. Mol. Brain Res.8:199-208(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"The GABAA receptor family: molecular and functional diversity."
Seeburg P.H. , Wisden W. , Verdoorn T. , Pritchett D. , Werner P. , Herb A. , Lueddens H. , Sprengel R. , Sakmann B.
Cold Spring Harb. Symp. Quant. Biol.55:29-40(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Brain.
5.

Groot-Kormelink P.J.
Submitted (2004-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
tissue: Brain.
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
7.

"Point mutations affecting antagonist affinity and agonist dependent gating of GABAA receptor channels."
Sigel E. , Baur R. , Kellenberger S. , Malherbe P.
EMBO J.11:2017-2023(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF PHE-91;FUNCTION;SUBCELLULAR LOCATION
8.

"GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1."
Bedford F.K. , Kittler J.T. , Muller E. , Thomas P. , Uren J.M. , Merlo D. , Wisden W. , Triller A. , Smart T.G. , Moss S.J.
Nat. Neurosci.4:908-916(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH UBQLN1
9.

"Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses."
Saras A. , Gisselmann G. , Vogt-Eisele A.K. , Erlkamp K.S. , Kletke O. , Pusch H. , Hatt H.
J. Biol. Chem.283:10470-10475(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;SUBUNIT

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