Protein name:
Gamma-aminobutyric acid receptor subunit beta-1 ;
Alternative:
GABA(A) receptor subunit beta-1 ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with KCTD8, KCTD12 and KCTD16; this interaction determines the pharmacology and kinetics of the receptor response, the KCTD proteins markedly accelerating the GABA-B response, although to different extents.
Function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subcellular Location:
Cell junction
synapse
postsynaptic cell membrane
Multi-pass membrane protein
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MWTVQNRESL | GLLSFPVMIA | MVCCAHSANE | PSNMSYVKET | VDRLLKGYDI |
100:
RLRPDFGGPP | VDVGMRIDVA | SIDMVSEVNM | DYTLTMYFQQ | SWKDKRLSYS |
150:
GIPLNLTLDN | RVADQLWVPD | TYFLNDKKSF | VHGVTVKNRM | IRLHPDGTVL |
200:
YGLRITTTAA | CMMDLRRYPL | DEQNCTLEIE | SYGYTTDDIE | FYWNGGEGAV |
250:
TGVNKIELPQ | FSIVDYKMVS | KKVEFTTGAY | PRLSLSFRLK | RNIGYFILQT |
300:
YMPSTLITIL | SWVSFWINYD | ASAARVALGI | TTVLTMTTIS | THLRETLPKI |
350:
PYVKAIDIYL | MGCFVFVFLA | LLEYAFVNYI | FFGKGPQKKG | AGKQDQSANE |
400:
KNKLEMNKVQ | VDAHGNILLS | TLEIRNETSG | SEVLTGVGDP | KTTMYSYDSA |
450:
SIQYRKPMSS | REGYGRALDR | HGAHSKGRIR | RRASQLKVKI | PDLTDVNSID |
474:
KWSRMFFPIT | FSLFNVVYWL | YYVH
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Bovine
Rat
ELISA Kit for Bovine Gamma-aminobutyric acid receptor subunit beta-1
ELISA Kit for Bovine Gamma-aminobutyric acid receptor subunit beta-1
ELISA Kit for Bovine Gamma-aminobutyric acid receptor subunit beta-1
ELISA Kit for Bovine Gamma-aminobutyric acid receptor subunit beta-1
CLIA Kit for Bovine Gamma-aminobutyric acid receptor subunit beta-1
CLIA Kit for Bovine Gamma-aminobutyric acid receptor subunit beta-1
CLIA Kit for Bovine Gamma-aminobutyric acid receptor subunit beta-1
CLIA Kit for Bovine Gamma-aminobutyric acid receptor subunit beta-1
Polyclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit beta-1
Polyclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit beta-1
Polyclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit beta-1
Polyclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit beta-1
Monoclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit beta-1
Monoclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit beta-1
Monoclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit beta-1
Monoclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit beta-1
Protein for Bovine Gamma-aminobutyric acid receptor subunit beta-1
Protein for Bovine Gamma-aminobutyric acid receptor subunit beta-1
Protein for Bovine Gamma-aminobutyric acid receptor subunit beta-1
Protein for Bovine Gamma-aminobutyric acid receptor subunit beta-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family."
Schofield P.R.
,
Darlison M.G.
,
Fujita N.
,
Burt D.R.
,
Stephenson F.A.
,
Rodriguez H.
,
Rhee L.M.
,
Ramachandran J.
,
Reale V.
,
Glencorse T.A.
,
Seeburg P.H.
,
Barnard E.A.
Nature328:221-227(1987)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;SUBUNIT
tissue :
Brain .