Gabrb1 ELISA Kit for Mouse(Mus musculus) | EIAab.comGabrb1 ELISA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Gabrb1(Gene name) > Mouse

Gabrb1 (Gene name),

Gamma-aminobutyric acid receptor subunit beta-1 (Protein name ), GBRB1_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Gabrb1;

Protein name:

Gamma-aminobutyric acid receptor subunit beta-1;

Alternative:

GABA(A) receptor subunit beta-1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Binds UBQLN1. Interacts with KCTD8, KCTD12, KCTD12B and KCTD16; this interaction determines the pharmacology and kinetics of the receptor response, the KCTD proteins markedly accelerating the GABA-B response, although to different extents.

Function:

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

Subcellular Location:

Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

474

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

474:

KWSRMFFPIT | FSLFNVVYWL | YYVH

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

UniGene:

Mm.38567

SMR:

P50571

String:

P50571

Pfam:

PF02931

STRING:

10090.ENSMUSP00000031122

KEGG:

mmu:14400

Uniprot:

P50571

FOR

ELISA Kit for Mouse Gamma-aminobutyric acid receptor subunit beta-1

CLIA Kit for Mouse Gamma-aminobutyric acid receptor subunit beta-1

Polyclonal Antibody for Mouse Gamma-aminobutyric acid receptor subunit beta-1

Monoclonal Antibody for Mouse Gamma-aminobutyric acid receptor subunit beta-1

Protein for Mouse Gamma-aminobutyric acid receptor subunit beta-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice."
Kamatchi G.L. , Kofuji P. , Wang J.B. , Fernando J.C. , Liu Z. , Mathura J.R. , Burt D.R.
Biochim. Biophys. Acta1261:134-142(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6J.
strain: DBA/2J.
tissue: Brain.
2.

"GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1."
Bedford F.K. , Kittler J.T. , Muller E. , Thomas P. , Uren J.M. , Merlo D. , Wisden W. , Triller A. , Smart T.G. , Moss S.J.
Nat. Neurosci.4:908-916(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH UBQLN1
3.

"Native GABA(B) receptors are heteromultimers with a family of auxiliary subunits."
Schwenk J. , Metz M. , Zolles G. , Turecek R. , Fritzius T. , Bildl W. , Tarusawa E. , Kulik A. , Unger A. , Ivankova K. , Seddik R. , Tiao J.Y. , Rajalu M. , Trojanova J. , Rohde V. , Gassmann M. , Schulte U. , Fakler B. , more...
Nature465:231-235(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KCTD8; KCTD12; KCTD12B AND KCTD16;FUNCTION;SUBCELLULAR LOCATION

Product Feedback Wall

* Email:
*Comments: