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Index > Protein center > Gabrg2(Gene name) > Mouse
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  • Gabrg2 (Gene name),
  • Gamma-aminobutyric acid receptor subunit gamma-2 (Protein name ),  GBRG2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Gabrg2;
    Protein name:
    Gamma-aminobutyric acid receptor subunit gamma-2;
    Alternative:
    GABA(A) receptor subunit gamma-2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.
    Function:
    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
    Subcellular Location:
    Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    474
    Sequence:
    50:
    MSSPNTWSIG | SSVYSPVFSQ | KMTLWILLLL | SLYPGFTSQK | SDDDYEDYAS | 
    100:
    NKTWVLTPKV | PEGDVTVILN | NLLEGYDNKL | RPDIGVKPTL | IHTDMYVNSI | 
    150:
    GPVNAINMEY | TIDIFFAQTW | YDRRLKFNST | IKVLRLNSNM | VGKIWIPDTF | 
    200:
    FRNSKKADAH | WITTPNRMLR | IWNDGRVLYT | LRLTIDAECQ | LQLHNFPMDE | 
    250:
    HSCPLEFSSY | GYPREEIVYQ | WKRSSVEVGD | TRSWRLYQFS | FVGLRNTTEV | 
    300:
    VKTTSGDYVV | MSVYFDLSRR | MGYFTIQTYI | PCTLIVVLSW | VSFWINKDAV | 
    350:
    PARTSLGITT | VLTMTTLSTI | ARKSLPKVSY | VTAMDLFVSV | CFIFVFSALV | 
    400:
    EYGTLHYFVS | NRKPSKDKDK | KKKNPLLRMF | SFKAPTIDIR | PRSATIQMNN | 
    450:
    ATHLQERDEE | YGYECLDGKD | CASFFCCFED | CRTGAWRHGR | IHIRIAKMDS | 
    474:
    YARIFFPTAF | CLFNLVYWVS | YLYL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    KEGG:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    ELISA Kit for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    ELISA Kit for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    ELISA Kit for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    ELISA Kit for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    CLIA Kit for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    CLIA Kit for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    CLIA Kit for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    CLIA Kit for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    CLIA Kit for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Polyclonal Antibody for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Polyclonal Antibody for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Polyclonal Antibody for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Polyclonal Antibody for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Polyclonal Antibody for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Monoclonal Antibody for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Monoclonal Antibody for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Monoclonal Antibody for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Monoclonal Antibody for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Monoclonal Antibody for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Protein for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Protein for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Protein for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Protein for Mouse Gamma-aminobutyric acid receptor subunit gamma-2
    Protein for Mouse Gamma-aminobutyric acid receptor subunit gamma-2

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    References
    1. 1.
      "Generation of two forms of the gamma-aminobutyric acidA receptor gamma 2-subunit in mice by alternative splicing."
      Kofuji P. , Wang J.B. , Moss S.J. , Huganir R.L. , Burt D.R.
      J. Neurochem.56:713-715(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2L AND 2S)
    2. 2.
      Sikela J.M. , Shaw W.D. , Khan A.S. , Lin L.-H. , Leidenheimer G. , Siegel R.E.
      Submitted (1991-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2L)
    3. 3.
      "Allelic variation in the GABA A receptor gamma2 subunit is associated with genetic susceptibility to ethanol-induced motor incoordination and hypothermia, conditioned taste aversion, and withdrawal in BXD/Ty recombinant inbred mice."
      Hood H.M. , Buck K.J.
      Alcohol. Clin. Exp. Res.24:1327-1334(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2L)
      strain: C57BL/6J.
      strain: DBA/2J.
      strain: Various BXD strains.
      tissue: Brain.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2L)
      tissue: Retina.
    5. 5.
      "The gamma2 subunit of GABA(A) receptors is a substrate for palmitoylation by GODZ."
      Keller C.A. , Yuan X. , Panzanelli P. , Martin M.L. , Alldred M. , Sassoe-Pognetto M. , Luescher B.
      J. Neurosci.24:5881-5891(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION
    6. 6.
      "Palmitoylation regulates the clustering and cell surface stability of GABAA receptors."
      Rathenberg J. , Kittler J.T. , Moss S.J.
      Mol. Cell. Neurosci.26:251-257(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION
    7. 7.
      "Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses."
      Saras A. , Gisselmann G. , Vogt-Eisele A.K. , Erlkamp K.S. , Kletke O. , Pusch H. , Hatt H.
      J. Biol. Chem.283:10470-10475(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;SUBUNIT
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