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Index > Protein center > GABARAPL1(Gene name) > Human
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  • GABARAPL1 (Gene name),
  • Gamma-aminobutyric acid receptor-associated protein-like 1 (Protein name ),  GBRL1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GABARAPL1(GEC1);
    Protein name:
    Gamma-aminobutyric acid receptor-associated protein-like 1;
    Alternative:
    GABA(A) receptor-associated protein-like 1;Early estrogen-regulated protein;Glandular epithelial cell protein 1(GEC-1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with GABRG2 and beta-tubulin (By similarity). Interacts with OPRK1.
    Function:
    Increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor.
    Subcellular Location:
    Cytoplasm cytoskeleton Membrane Endoplasmic reticulum Golgi apparatus
    Protein Attributes:
    Sequence length:
    117
    Sequence:
    50:
    MKFQYKEDHP | FEYRKKEGEK | IRKKYPDRVP | VIVEKAPKAR | VPDLDKRKYL | 
    100:
    VPSDLTVGQF | YFLIRKRIHL | RPEDALFFFV | NNTIPPTSAT | MGQLYEDNHE | 
    117:
    EDYFLYVAYS | DESVYGK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    MIM:
    String:
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    ELISA Kit for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    ELISA Kit for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    ELISA Kit for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    CLIA Kit for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    CLIA Kit for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    CLIA Kit for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    CLIA Kit for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    Polyclonal Antibody for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    Polyclonal Antibody for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    Polyclonal Antibody for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    Polyclonal Antibody for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    Monoclonal Antibody for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    Monoclonal Antibody for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    Monoclonal Antibody for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    Monoclonal Antibody for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    Protein for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    Protein for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    Protein for Human Gamma-aminobutyric acid receptor-associated protein-like 1
    Protein for Human Gamma-aminobutyric acid receptor-associated protein-like 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
      tissue: Placenta.
    2. 2.
      "Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABA(A) receptor-associated protein."
      Xin Y. , Yu L. , Chen Z. , Zheng L. , Fu Q. , Jiang J. , Zhang P. , Gong R. , Zhao S.
      Genomics74:408-413(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
    3. 3.
      "Alternative splicing pattern analysis of human Atg8 family proteins."
      Liu C. , Yu L.
      Submitted (2011-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Thymus.
    6. 6.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    7. 7.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
      tissue: Colon.
    10. 10.
      "GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor."
      Chen C. , Li J.-G. , Chen Y. , Huang P. , Wang Y. , Liu-Chen L.-Y.
      J. Biol. Chem.281:7983-7993(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH OPRK1
    11. 11.
      "p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy."
      Pankiv S. , Clausen T.H. , Lamark T. , Brech A. , Bruun J.A. , Outzen H. , Overvatn A. , Bjorkoy G. , Johansen T.
      J. Biol. Chem.282:24131-24145(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SQSTM1;SUBCELLULAR LOCATION
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;PROTEOLYTIC CLEAVAGE;LIPIDATION AT GLY-116;MUTAGENESIS OF GLY-116
    13. 13.
      "Network organization of the human autophagy system."
      Behrends C. , Sowa M.E. , Gygi S.P. , Harper J.W.
      Nature466:68-76(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TECPR2
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      "MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins."
      Colecchia D. , Strambi A. , Sanzone S. , Iavarone C. , Rossi M. , Dall'Armi C. , Piccioni F. , Verrotti di Pianella A. , Chiariello M.
      Autophagy8:1724-1740(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MAPK15
    16. 16.
      "ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs."
      Alemu E.A. , Lamark T. , Torgersen K.M. , Birgisdottir A.B. , Larsen K.B. , Jain A. , Olsvik H. , Overvatn A. , Kirkin V. , Johansen T.
      J. Biol. Chem.287:39275-39290(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATG13; RB1CC1 AND ULK1
    17. 17.
      "Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers."
      Popovic D. , Akutsu M. , Novak I. , Harper J.W. , Behrends C. , Dikic I.
      Mol. Cell. Biol.32:1733-1744(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TBC1D5
    18. 18.
      "DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription."
      Sancho A. , Duran J. , Garcia-Espana A. , Mauvezin C. , Alemu E.A. , Lamark T. , Macias M.J. , Desalle R. , Royo M. , Sala D. , Chicote J.U. , Palacin M. , Johansen T. , Zorzano A.
      PLoS ONE7:E34034-E34034(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TP53INP1 AND TP53INP2
    19. 19.
      "The Legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation."
      Choy A. , Dancourt J. , Mugo B. , O'Connor T.J. , Isberg R.R. , Melia T.J. , Roy C.R.
      Science338:1072-1076(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DECONJUGATION BY LEGIONELLA RAVZ
    20. 20.
      "Specific distribution of the autophagic protein GABARAPL1/GEC1 in the developing and adult mouse brain and identification of neuronal populations expressing GABARAPL1/GEC1."
      Le Grand J.N. , Bon K. , Fraichard A. , Zhang J. , Jouvenot M. , Risold P.Y. , Boyer-Guittaut M. , Delage-Mourroux R.
      PLoS ONE8:E63133-E63133(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    21. 21.
      "Crystal structure of human gamma-aminobutyric acid receptor-associated protein-like 1 (GABARAP1)."
      Structural genomics consortium (SGC)
      Submitted (2007-09) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) OF 3-111
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