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Index > Protein center > GABRR1(Gene name) > Human
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  • GABRR1 (Gene name),
  • Gamma-aminobutyric acid receptor subunit rho-1 (Protein name ),  GBRR1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GABRR1;
    Protein name:
    Gamma-aminobutyric acid receptor subunit rho-1;
    Alternative:
    GABA(C) receptor;GABA(A) receptor subunit rho-1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
    Function:
    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.
    Subcellular Location:
    Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    479
    Sequence:
    50:
    MLAVPNMRFG | IFLLWWGWVL | ATESRMHWPG | REVHEMSKKG | RPQRQRREVH | 
    100:
    EDAHKQVSPI | LRRSPDITKS | PLTKSEQLLR | IDDHDFSMRP | GFGGPAIPVG | 
    150:
    VDVQVESLDS | ISEVDMDFTM | TLYLRHYWKD | ERLSFPSTNN | LSMTFDGRLV | 
    200:
    KKIWVPDMFF | VHSKRSFIHD | TTTDNVMLRV | QPDGKVLYSL | RVTVTAMCNM | 
    250:
    DFSRFPLDTQ | TCSLEIESYA | YTEDDLMLYW | KKGNDSLKTD | ERISLSQFLI | 
    300:
    QEFHTTTKLA | FYSSTGWYNR | LYINFTLRRH | IFFFLLQTYF | PATLMVMLSW | 
    350:
    VSFWIDRRAV | PARVPLGITT | VLTMSTIITG | VNASMPRVSY | IKAVDIYLWV | 
    400:
    SFVFVFLSVL | EYAAVNYLTT | VQERKEQKLR | EKLPCTSGLP | PPRTAMLDGN | 
    450:
    YSDGEVNDLD | NYMPENGEKP | DRMMVQLTLA | SERSSPQRKS | QRSSYVSMRI | 
    479:
    DTHAIDKYSR | IIFPAAYILF | NLIYWSIFS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    UniGene:
    Pfam:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Gamma-aminobutyric acid receptor subunit rho-1
    ELISA Kit for Human Gamma-aminobutyric acid receptor subunit rho-1
    ELISA Kit for Human Gamma-aminobutyric acid receptor subunit rho-1
    CLIA Kit for Human Gamma-aminobutyric acid receptor subunit rho-1
    CLIA Kit for Human Gamma-aminobutyric acid receptor subunit rho-1
    CLIA Kit for Human Gamma-aminobutyric acid receptor subunit rho-1
    Polyclonal Antibody for Human Gamma-aminobutyric acid receptor subunit rho-1
    Polyclonal Antibody for Human Gamma-aminobutyric acid receptor subunit rho-1
    Polyclonal Antibody for Human Gamma-aminobutyric acid receptor subunit rho-1
    Monoclonal Antibody for Human Gamma-aminobutyric acid receptor subunit rho-1
    Monoclonal Antibody for Human Gamma-aminobutyric acid receptor subunit rho-1
    Monoclonal Antibody for Human Gamma-aminobutyric acid receptor subunit rho-1
    Protein for Human Gamma-aminobutyric acid receptor subunit rho-1
    Protein for Human Gamma-aminobutyric acid receptor subunit rho-1
    Protein for Human Gamma-aminobutyric acid receptor subunit rho-1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina."
      Cutting G.R. , Lu L. , O'Hara B.F. , Kasch L.M. , Montrose-Rafizadeh C. , Donovan D.M. , Shimada S. , Antonarakis S.E. , Guggino W.B. , Uhl G.R. , Kazazian H.H. Jr.
      Proc. Natl. Acad. Sci. U.S.A.88:2673-2677(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Retina.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3);VARIANT VAL-26
      tissue: Thalamus.
    3. 3.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
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