Protein name:
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 ;
Alternative:
dI/C2/C4GnT (dIGnT) ;C2GnT-mucin type (C2GnT-M) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.
Subcellular Location:
Golgi apparatus membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MVSWRRFCWH | YHGWTLGCYM | LLAIIALKLS | LRLKCDFDVM | DLDSKEFQSQ |
100:
YCRDLLYKTL | ELPAKSSINC | SGVIRGEQKA | VTQALLNNLE | LKRKRQSFTE |
150:
ADYLSMTADC | EHFKTQRKFI | QVPLSKEEAN | FPIAYSMVIH | EKIENFERLL |
200:
RAVYTPQNIY | CVHVDQKSSE | TFQQAVRAIV | SCFPNVFIAN | KLVSVVYASW |
250:
SRVQADLNCM | EDLLQSPVPW | EYLLNTCGTD | FPIKTNAEMV | KALKLLNGQN |
300:
SMESEVPPPH | KTFRWKYHYE | VADTLYRTSK | EKTPPPNNIT | MFTGNAYMVA |
350:
SRDFIEHVLS | NSKARQLIEW | VKDTYSPDEH | LWATLQRASW | MPGSDPLHPK |
400:
FDLSDMRSIA | RLTKWQDHEG | DIENGAPYTS | CSGIHQRAIC | VYGSGDLHWI |
437:
LQNHHLLANK | FDPKVDDNVL | QCLEEYLRHK | AIYGTEL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Rat
Human
ELISA Kit for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
ELISA Kit for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
ELISA Kit for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
ELISA Kit for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
CLIA Kit for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
CLIA Kit for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
CLIA Kit for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
CLIA Kit for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Polyclonal Antibody for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Polyclonal Antibody for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Polyclonal Antibody for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Polyclonal Antibody for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Monoclonal Antibody for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Monoclonal Antibody for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Monoclonal Antibody for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Monoclonal Antibody for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Protein for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Protein for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Protein for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Protein for Rat Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Purification and cDNA cloning of UDP-GlcNAc:GlcNAcbeta1-3Galbeta1-4Glc(NAc)-R [GlcNAc to Gal]beta1,6N-acetylglucosaminyltransferase from rat small intestine: a major carrier of dIGnT activity in rat small intestine."
Korekane H.
,
Taguchi T.
,
Sakamoto Y.
,
Honke K.
,
Dohmae N.
,
Salminen H.
,
Toivonen S.
,
Helin J.
,
Takio K.
,
Renkonen O.
,
Taniguchi N.
Glycobiology13:387-400(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 118-126; 266-280 AND 313-324;BIOPHYSICOCHEMICAL PROPERTIES