Protein name:
Gem-associated protein 6 (Gemin-6) ;
Alternative:
SIP2 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Part of the core SMN complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8 and STRAP/UNRIP. Interacts directly with GEMIN7, SNRPB, SNRPD2, SNRPD3 and SNRPE.
Function:
The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.
Subcellular Location:
Nucleus
nucleoplasm
Nucleus
gem
Cytoplasm
Found both in the nucleoplasm and in nuclear bodies called gems (Gemini of Cajal bodies) that are often in proximity to Cajal (coiled) bodies. Also found in the cytoplasm.
Protein Attributes:
50:
MSEWMKKGPL | EWQDYIYKEV | RVTASEKNEY | KGWVLTTDPV | SANIVLVNFL |
100:
EDGSMSVTGI | MGHAVQTVET | MNEGDHRVRE | KLMHLFTSGD | CKAYSPEDLE |
150:
ERKNSLKKWL | EKNHIPITEQ | GDAPRTLCVA | GVLTIDPPYG | PENCSSSNEI |
167:
ILSRVQDLIE | GHLTASQ
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
ELISA Kit for Human Gemin-6
ELISA Kit for Human Gemin-6
ELISA Kit for Human Gemin-6
CLIA Kit for Human Gemin-6
CLIA Kit for Human Gemin-6
CLIA Kit for Human Gemin-6
Polyclonal Antibody for Human Gemin-6
Polyclonal Antibody for Human Gemin-6
Polyclonal Antibody for Human Gemin-6
Monoclonal Antibody for Human Gemin-6
Monoclonal Antibody for Human Gemin-6
Monoclonal Antibody for Human Gemin-6
Protein for Human Gemin-6
Protein for Human Gemin-6
Protein for Human Gemin-6
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 155-167;FUNCTION;INTERACTION WITH SNRPB; SNRPD2; SNRPD3 AND SNRPE;SUBCELLULAR LOCATION
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ASP-140
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Ovary .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH GEMIN7
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cervix carcinoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-166;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cervix carcinoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 1-86 IN COMPLEX WITH GEMIN7;INTERACTION WITH SNRPB; SNRPD2; SNRPD3 AND SNRPE