Protein name:
GDNF family receptor alpha-4 (GDNF receptor alpha-4;GDNFR-alpha-4;GFR-alpha-4) ;
Alternative:
Persephin receptor ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
Subcellular Location:
Isoform B
Secreted
Protein Attributes:
50:
MLSGAYLRVL | NERPGQAVLW | SLGCQRGSAS | STEGNRCVEA | AEACTADEQC |
100:
QQLRSEYVAQ | CLGRAGWRGP | GSCVRSRCRR | ALRRFFARGP | PALTHALLFC |
150:
GCEGPACAER | RRQTFAPACA | FSGPQLAPPS | CLKPLDRCER | SRRCRPRLFA |
200:
FQASCAPAPG | SRDGCPEEGG | PRCLRAYAGL | VGTVVTPNYL | DNVSARVAPW |
250:
CGCEASGNRR | EECEAFRKLF | TRNPCLDGAI | QAFDSSQPSV | LQDQWNPYQN |
273:
AGCCFLWVSS | MSILTALALQ | ALL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Mouse
Rat
Human
ELISA Kit for Rat GDNF receptor alpha-4
ELISA Kit for Rat GDNF receptor alpha-4
ELISA Kit for Rat GDNF receptor alpha-4
ELISA Kit for Rat GDNF receptor alpha-4
CLIA Kit for Rat GDNF receptor alpha-4
CLIA Kit for Rat GDNF receptor alpha-4
CLIA Kit for Rat GDNF receptor alpha-4
CLIA Kit for Rat GDNF receptor alpha-4
Polyclonal Antibody for Rat GDNF receptor alpha-4
Polyclonal Antibody for Rat GDNF receptor alpha-4
Polyclonal Antibody for Rat GDNF receptor alpha-4
Polyclonal Antibody for Rat GDNF receptor alpha-4
Monoclonal Antibody for Rat GDNF receptor alpha-4
Monoclonal Antibody for Rat GDNF receptor alpha-4
Monoclonal Antibody for Rat GDNF receptor alpha-4
Monoclonal Antibody for Rat GDNF receptor alpha-4
Protein for Rat GDNF receptor alpha-4
Protein for Rat GDNF receptor alpha-4
Protein for Rat GDNF receptor alpha-4
Protein for Rat GDNF receptor alpha-4
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Mammalian GFRalpha-4, a divergent member of the GFRalpha family of coreceptors for glial cell line-derived neurotrophic factor family ligands, is a receptor for the neurotrophic factor persephin."
Masure S.
,
Cik M.
,
Hoefnagel E.
,
Nosrat C.A.
,
Van der Linden I.
,
Scott R.
,
Van Gompel P.
,
Lesage A.S.J.
,
Verhasselt P.
,
Ibanez C.F.
,
Gordon R.D.
J. Biol. Chem.275:39427-39434(2000)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A AND B);VARIANT ARG-257
tissue :
Brain .
tissue :
Heart .
tissue :
Kidney .