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Index > Protein center > Ggt1(Gene name) > Mouse
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  • Ggt1 (Gene name),
  • Gamma-glutamyltranspeptidase 1 (Protein name ),  GGT1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Ggt1(Ggt;Ggtp);
    Protein name:
    Gamma-glutamyltranspeptidase 1(GGT 1);
    Alternative:
    3.4.19.13;Glutathione hydrolase 1);Gamma-glutamyltransferase 1;3.4.19.14;Leukotriene-C4 hydrolase);
    CD:
    CD224;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterodimer composed of the light and heavy chains. The active site is located in the light chain.
    Function:
    Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Indirectly regulates mutiple aspects of skeletal biology.
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    568
    Sequence:
    50:
    MKNRFLVLGL | VAVVLVFVII | GLCIWLPYTS | GKPDHVYSRA | AVATDAKRCS | 
    100:
    EIGRDILQEG | GSVVDAAIAS | LLCMGLMNAH | SMGIGGGLFF | TIYNSTTGKV | 
    150:
    EVINAREVAP | RLANTTMFNN | SKDSEEGGLS | VAVPGEIRGY | ELAHQRHGRL | 
    200:
    PWARLFQPSI | QLARHGFPVG | KGLAIALDKK | RDVIEKTPAL | CEVFCRQGKV | 
    250:
    LQEGETVTMP | KLADTLQILA | QEGAKAFYNG | SLTAQIVKDI | QEAGGIMTVE | 
    300:
    DLNNYRAELI | EHPMSIGLGD | ATLYVPSAPL | SGPVLILILN | ILKGYNFSPK | 
    350:
    SVATPEQKAL | TYHRIVEAFR | FAYAKRTMLG | DPKFVDVSQV | IRNMSSEFYA | 
    400:
    TQLRARITDE | TTHPAAYYEP | EFYLQDDGGT | AHLSAVSEDG | SAVAATSTIN | 
    450:
    LYFGSKVLSR | VSGILFNDEM | DDFSSPNFIN | QFRVAPSPAN | FIKPGKQPLS | 
    500:
    SMCPSIILDK | DGQVRMVVGA | SGGTQITTSV | ALAIINSLWF | GYDVKRAVEE | 
    550:
    PRLHNQLLPN | TTTVEKDIDQ | VVTAGLKIRH | HHTEVTPTFI | AVVQAVVRAS | 
    568:
    GGWAAASDSR | KGGEPAGY
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    UniGene:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse GGT 1
    Cat.:
    E1375h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse GGT 1
    Cat.:
    E1375m
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    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse GGT 1
    Cat.:
    E1375r
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    MSDS:
    Please sign in first.
    Packing:
    96T
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    ELISA Kit for Mouse GGT 1
    Cat.:
    E1375p
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse GGT 1
    Cat.:
    U1375r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse GGT 1
    Cat.:
    U1375p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse GGT 1
    Cat.:
    U1375m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse GGT 1
    Cat.:
    U1375h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse GGT 1
    Cat.:
    P1375Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse GGT 1
    Cat.:
    P1375Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse GGT 1
    Cat.:
    P1375Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse GGT 1
    Monoclonal Antibody for Mouse GGT 1
    Monoclonal Antibody for Mouse GGT 1
    Monoclonal Antibody for Mouse GGT 1
    Monoclonal Antibody for Mouse GGT 1
    Protein for Mouse GGT 1
    Protein for Mouse GGT 1
    Protein for Mouse GGT 1
    Protein for Mouse GGT 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene."
      Shi Z.Z. , Habib G.M. , Lebovitz R.M. , Lieberman M.W.
      Gene167:233-237(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6.
      tissue: Kidney.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Mammary tumor.
    3. 3.
      "Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species."
      Chikhi N. , Holic N. , Guellaen G. , Laperche Y.
      Comp. Biochem. Physiol.122B:367-380(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GENE ORGANIZATION;ALTERNATIVE PROMOTER USAGE
    4. 4.
      "Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility."
      Harding C.O. , Williams P. , Wagner E. , Chang D.S. , Wild K. , Colwell R.E. , Wolff J.A.
      J. Biol. Chem.272:12560-12567(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISEASE
    5. 5.
      "Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice."
      Levasseur R. , Barrios R. , Elefteriou F. , Glass D.A. II , Lieberman M.W. , Karsenty G.
      Endocrinology144:2761-2764(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISEASE;FUNCTION
    6. 6.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-114; ASN-120; ASN-229 AND ASN-510
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