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Index > Protein center > GLCE(Gene name) > Human
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  • GLCE (Gene name),
  • D-glucuronyl C5-epimerase (Protein name ),  GLCE_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    GLCE(KIAA0836);
    Protein name:
    D-glucuronyl C5-epimerase;
    Alternative:
    Heparin/heparan sulfate:glucuronic acid C5-epimerase;Heparin/heparan sulfate:glucuronic acid C5-epimerase(Hsepi);Heparosan-N-sulfate-glucuronate 5-epimerase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with HS2ST1.
    Function:
    Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acids.
    Subcellular Location:
    Golgi apparatus membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    617
    Sequence:
    50:
    MRCLAARVNY | KTLIIICALF | TLVTVLLWNK | CSSDKAIQFP | RRSSSGFRVD | 
    100:
    GFEKRAAASE | SNNYMNHVAK | QQSEEAFPQE | QQKAPPVVGG | FNSNVGSKVL | 
    150:
    GLKYEEIDCL | INDEHTIKGR | REGNEVFLPF | TWVEKYFDVY | GKVVQYDGYD | 
    200:
    RFEFSHSYSK | VYAQRAPYHP | DGVFMSFEGY | NVEVRDRVKC | ISGVEGVPLS | 
    250:
    TQWGPQGYFY | PIQIAQYGLS | HYSKNLTEKP | PHIEVYETAE | DRDKNKPNDW | 
    300:
    TVPKGCFMAN | VADKSRFTNV | KQFIAPETSE | GVSLQLGNTK | DFIISFDLKF | 
    350:
    LTNGSVSVVL | ETTEKNQLFT | IHYVSNAQLI | AFKERDIYYG | IGPRTSWSTV | 
    400:
    TRDLVTDLRK | GVGLSNTKAV | KPTKIMPKKV | VRLIAKGKGF | LDNITISTTA | 
    450:
    HMAAFFAASD | WLVRNQDEKG | GWPIMVTRKL | GEGFKSLEPG | WYSAMAQGQA | 
    500:
    ISTLVRAYLL | TKDHIFLNSA | LRATAPYKFL | SEQHGVKAVF | MNKHDWYEEY | 
    550:
    PTTPSSFVLN | GFMYSLIGLY | DLKETAGEKL | GKEARSLYER | GMESLKAMLP | 
    600:
    LYDTGSGTIY | DLRHFMLGIA | PNLARWDYHT | THINQLQLLS | TIDESPVFKE | 
    617:
    FVKRWKSYLK | GSRAKHN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human D-glucuronyl C5-epimerase
    ELISA Kit for Human D-glucuronyl C5-epimerase
    ELISA Kit for Human D-glucuronyl C5-epimerase
    CLIA Kit for Human D-glucuronyl C5-epimerase
    CLIA Kit for Human D-glucuronyl C5-epimerase
    CLIA Kit for Human D-glucuronyl C5-epimerase
    Polyclonal Antibody for Human D-glucuronyl C5-epimerase
    Polyclonal Antibody for Human D-glucuronyl C5-epimerase
    Polyclonal Antibody for Human D-glucuronyl C5-epimerase
    Monoclonal Antibody for Human D-glucuronyl C5-epimerase
    Monoclonal Antibody for Human D-glucuronyl C5-epimerase
    Monoclonal Antibody for Human D-glucuronyl C5-epimerase
    Protein for Human D-glucuronyl C5-epimerase
    Protein for Human D-glucuronyl C5-epimerase
    Protein for Human D-glucuronyl C5-epimerase

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Homo sapiens D-glucuronyl C5-epimerase (GLCE)."
      Ghiselli G.
      Submitted (2004-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 3.
      "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Ishikawa K. , Suyama M. , Kikuno R. , Hirosawa M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
      DNA Res.5:355-364(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 9-617;VARIANT ILE-597
      tissue: Brain.
    3. 4.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-225
      tissue: Liver.
    4. 5.
      "Using engineered 2-O-sulfotransferase to determine the activity of heparan sulfate C5-epimerase and its mutants."
      Li K. , Bethea H.N. , Liu J.
      J. Biol. Chem.285:11106-11113(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;FUNCTION;MUTAGENESIS OF TYR-146; TYR-162; TYR-168; TYR-210 AND TYR-222
    5. 6.
      "Uncovering a biphasic catalytic mode of C5-epimerase in heparan sulfate biosynthesis."
      Sheng J. , Xu Y. , Dulaney S.B. , Huang X. , Liu J.
      J. Biol. Chem.287:20996-21002(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY
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