Glce ELISA Kit for Mouse(Mus musculus) | EIAab.comGlce ELISA Kit for Mouse(Mus musculus)

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Glce (Gene name),

D-glucuronyl C5-epimerase (Protein name ), GLCE_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Glce;

Protein name:

D-glucuronyl C5-epimerase;

Alternative:

Heparin sulfate C5-epimerase;Heparin/heparan sulfate:glucuronic acid C5-epimerase(Hsepi);Heparosan-N-sulfate-glucuronate 5-epimerase;Heparin/heparan sulfate:glucuronic acid C5-epimerase;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with HS2ST1.

Function:

Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acids.

Subcellular Location:

Golgi apparatus membrane Single-pass type II membrane protein

Protein Attributes:

Sequence length:

618

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

618:

EFVKRWKSYL | KGSRAKHN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF06662

UniGene:

Mm.24411

KEGG:

mmu:93683

String:

Q9EPS3

Uniprot:

Q9EPS3

FOR

ELISA Kit for Mouse D-glucuronyl C5-epimerase

CLIA Kit for Mouse D-glucuronyl C5-epimerase

Polyclonal Antibody for Mouse D-glucuronyl C5-epimerase

Monoclonal Antibody for Mouse D-glucuronyl C5-epimerase

Protein for Mouse D-glucuronyl C5-epimerase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Characterization of the D-glucuronyl C5-epimerase involved in the biosynthesis of heparin and heparan sulfate."
Li J.-P. , Gong F. , El Darwish K. , Jalkanen M. , Lindahl U.
J. Biol. Chem.276:20069-20077(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;FUNCTION
strain: BALB/c.
tissue: Liver.
tissue: Mast cell.
2.

"Cloning, Golgi localization, and enzyme activity of the full-length heparin/heparan sulfate-glucuronic acid C5-epimerase."
Crawford B.E. , Olson S.K. , Esko J.D. , Pinhal M.A.S.
J. Biol. Chem.276:21538-21543(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CATALYTIC ACTIVITY;FUNCTION;SUBCELLULAR LOCATION
tissue: Mast cell.
3.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
tissue: Brain.
5.

"Enzyme interactions in heparan sulfate biosynthesis: uronosyl 5-epimerase and 2-O-sulfotransferase interact in vivo."
Pinhal M.A.S. , Smith B. , Olson S. , Aikawa J. , Kimata K. , Esko J.D.
Proc. Natl. Acad. Sci. U.S.A.98:12984-12989(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HS2ST1
6.

"Targeted disruption of a murine glucuronyl C5-epimerase gene results in heparan sulfate lacking L-iduronic acid and in neonatal lethality."
Li J.P. , Gong F. , Hagner-McWhirter A. , Forsberg E. , Abrink M. , Kisilevsky R. , Zhang X. , Lindahl U.
J. Biol. Chem.278:28363-28366(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
7.

"Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells."
Feyerabend T.B. , Li J.P. , Lindahl U. , Rodewald H.R.
Nat. Chem. Biol.2:195-196(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;FUNCTION
8.

"Impaired lymphoid organ development in mice lacking the heparan sulfate modifying enzyme glucuronyl C5-epimerase."
Reijmers R.M. , Vondenhoff M.F. , Roozendaal R. , Kuil A. , Li J.P. , Spaargaren M. , Pals S.T. , Mebius R.E.
J. Immunol.184:3656-3664(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION

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