Glis2 ELISA Kit for Mouse(Mus musculus) | EIAab.comGlis2 ELISA Kit for Mouse(Mus musculus)

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Glis2 (Gene name),

Zinc finger protein GLIS2 (Protein name ), GLIS2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Glis2(Gli5;Nkl);

Protein name:

Zinc finger protein GLIS2;

Alternative:

Neuronal Krueppel-like protein;GLI-similar 2;Zinc finger protein GLI5;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with CTBP1 and HDAC3. Interacts with CTNNB1 and CTNND1.

Function:

Can act either as a transcription repressor or as a transcription activator, depending on the cell context. Represses the transcriptional activation mediated by CTNNB1 in the Wnt pathway. May act by recruiting the corepressors CTBP1 and HDAC3. May be involved in neuron differentiation.

Subcellular Location:

Nucleus speckle Cytoplasm

Protein Attributes:

Sequence length:

521

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

521:

LTPGWVVIPP | GSVLLKPAVV | N

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q8VDL9

KEGG:

mmu:83396

UniGene:

Mm.134072

String:

Q8VDL9

Pfam:

PF00096

Uniprot:

Q8VDL9

FOR

ELISA Kit for Mouse Zinc finger protein GLIS2

CLIA Kit for Mouse Zinc finger protein GLIS2

Polyclonal Antibody for Mouse Zinc finger protein GLIS2

Monoclonal Antibody for Mouse Zinc finger protein GLIS2

Protein for Mouse Zinc finger protein GLIS2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal differentiation."
Lamar E. , Kintner C. , Goulding M.
Development128:1335-1346(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];DEVELOPMENTAL STAGE;FUNCTION
2.

"Characterization of Glis2, a novel gene encoding a Gli-related, Kruppel-like transcription factor with transactivation and repressor functions. Roles in kidney development and neurogenesis."
Zhang F. , Nakanishi G. , Kurebayashi S. , Yoshino K. , Perantoni A. , Kim Y.-S. , Jetten A.M.
J. Biol. Chem.277:10139-10149(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY;FUNCTION
strain: 129/SvJ.
strain: BALB/c.
tissue: Kidney.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Mammary tumor.
4.

"Kruppel-like zinc finger protein Gli-similar 2 (Glis2) represses transcription through interaction with C-terminal binding protein 1 (CtBP1)."
Kim S.-C. , Kim Y.-S. , Jetten A.M.
Nucleic Acids Res.33:6805-6815(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CTBP1 AND HDAC3;CLEAVAGE;SUBCELLULAR LOCATION
5.

"The Kruppel-like zinc finger protein Glis2 functions as a negative modulator of the Wnt/beta-catenin signaling pathway."
Kim Y.-S. , Kang H.S. , Jetten A.M.
FEBS Lett.581:858-864(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CTNNB1;MUTAGENESIS OF CYS-175;SUBCELLULAR LOCATION
6.

"The transcriptional repressor Glis2 is a novel binding partner for p120 catenin."
Hosking C.R. , Ulloa F. , Hogan C. , Ferber E.C. , Figueroa A. , Gevaert K. , Birchmeier W. , Briscoe J. , Fujita Y.
Mol. Biol. Cell18:1918-1927(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CTNND1;CLEAVAGE SITE;DNA-BINDING;SUBCELLULAR LOCATION;MUTAGENESIS OF CYS-170; TYR-288 AND ASP-290
7.

"Increased hedgehog signaling in postnatal kidney results in aberrant activation of nephron developmental programs."
Li B. , Rauhauser A.A. , Dai J. , Sakthivel R. , Igarashi P. , Jetten A.M. , Attanasio M.
Hum. Mol. Genet.20:4155-4166(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SUFU

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