Gls ELISA Kit for Mouse(Mus musculus) | EIAab.comGls ELISA Kit for Mouse(Mus musculus)

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Gls (Gene name),

Glutaminase kidney isoform, mitochondrial (Protein name ), GLSK_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Gls(Gls1;Kiaa0838);

Protein name:

Glutaminase kidney isoform, mitochondrial(GLS);

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homotetramer. Interacts with ATCAY; the interaction is direct and may control GLS localization, negatively regulating its activity.

Function:

Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain.

Subcellular Location:

Isoform 2 Mitochondrion

Protein Attributes:

Sequence length:

674

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

674:

YTPQGDSDDG | KGNQTVHKNL | DGLL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

D3Z7P3

UniGene:

Mm.398608

KEGG:

mmu:14660

Pfam:

PF12796

STRING:

10090.ENSMUSP00000110158

Uniprot:

D3Z7P3

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ELISA Kit for Mouse GLS

Cat.:

E15055h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Mouse GLS

MSDS:

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ELISA Kit for Mouse GLS

MSDS:

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CLIA Kit for Mouse GLS

MSDS:

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CLIA Kit for Mouse GLS

MSDS:

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CLIA Kit for Mouse GLS

Cat.:

U15055h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse GLS

Monoclonal Antibody for Mouse GLS

Protein for Mouse GLS

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Seino S. , Nishimura M. , Kaisho T. , Hoshino K. , Kitamura H. , Nagase T. , Ohara O. , Koga H.
DNA Res.11:205-218(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Embryonic tail.
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];ALTERNATIVE SPLICING
strain: C57BL/6J.
3.

"Brain-specific BNIP-2-homology protein Caytaxin relocalises glutaminase to neurite terminals and reduces glutamate levels."
Buschdorf J.P. , Li Chew L. , Zhang B. , Cao Q. , Liang F.Y. , Liou Y.C. , Zhou Y.T. , Low B.C.
J. Cell Sci.119:3337-3350(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATCAY
4.

"Mice lacking brain/kidney phosphate-activated glutaminase have impaired glutamatergic synaptic transmission, altered breathing, disorganized goal-directed behavior and die shortly after birth."
Masson J. , Darmon M. , Conjard A. , Chuhma N. , Ropert N. , Thoby-Brisson M. , Foutz A.S. , Parrot S. , Miller G.M. , Jorisch R. , Polan J. , Hamon M. , Hen R. , Rayport S.
J. Neurosci.26:4660-4671(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION;SUBCELLULAR LOCATION
5.

"Brain slices from glutaminase-deficient mice metabolize less glutamine: a cellular metabolomic study with carbon 13 NMR."
El Hage M. , Masson J. , Conjard-Duplany A. , Ferrier B. , Baverel G. , Martin G.
J. Cereb. Blood Flow Metab.32:816-824(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-135 AND LYS-169;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.
7.

"Mitochondrial localization and structure-based phosphate activation mechanism of glutaminase C with implications for cancer metabolism."
Cassago A. , Ferreira A.P. , Ferreira I.M. , Fornezari C. , Gomes E.R. , Greene K.S. , Pereira H.M. , Garratt R.C. , Dias S.M. , Ambrosio A.L.
Proc. Natl. Acad. Sci. U.S.A.109:1092-1097(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.42 ANGSTROMS) OF 128-555 (ISOFORM 2) IN COMPLEX WITH GLUTAMATE AND PHOSPHATE;FUNCTION;CATALYTIC ACTIVITY;ENZYME REGULATION;ALTERNATIVE SPLICING;MUTAGENESIS OF PHE-394;SUBUNIT

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