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Index > Protein center > SHMT2(Gene name) > Human
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  • SHMT2 (Gene name),
  • Serine hydroxymethyltransferase, mitochondrial (Protein name ),  GLYM_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SHMT2;
    Protein name:
    Serine hydroxymethyltransferase, mitochondrial(SHMT);
    Alternative:
    Serine methylase;Glycine hydroxymethyltransferase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer.
    Function:
    Interconversion of serine and glycine. Associates with mitochondrial DNA.
    Subcellular Location:
    Mitochondrion Mitochondrion matrix mitochondrion nucleoid
    Protein Attributes:
    Sequence length:
    504
    Sequence:
    50:
    MLYFSLFWAA | RPLQRCGQLV | RMAIRAQHSN | AAQTQTGEAN | RGWTGQESLS | 
    100:
    DSDPEMWELL | QREKDRQCRG | LELIASENFC | SRAALEALGS | CLNNKYSEGY | 
    150:
    PGKRYYGGAE | VVDEIELLCQ | RRALEAFDLD | PAQWGVNVQP | YSGSPANLAV | 
    200:
    YTALLQPHDR | IMGLDLPDGG | HLTHGYMSDV | KRISATSIFF | ESMPYKLNPK | 
    250:
    TGLIDYNQLA | LTARLFRPRL | IIAGTSAYAR | LIDYARMREV | CDEVKAHLLA | 
    300:
    DMAHISGLVA | AKVIPSPFKH | ADIVTTTTHK | TLRGARSGLI | FYRKGVKAVD | 
    350:
    PKTGREIPYT | FEDRINFAVF | PSLQGGPHNH | AIAAVAVALK | QACTPMFREY | 
    400:
    SLQVLKNARA | MADALLERGY | SLVSGGTDNH | LVLVDLRPKG | LDGARAERVL | 
    450:
    ELVSITANKN | TCPGDRSAIT | PGGLRLGAPA | LTSRQFREDD | FRRVVDFIDE | 
    500:
    GVNIGLEVKS | KTAKLQDFKS | FLLKDSETSQ | RLANLRQRVE | QFARAFPMPG | 
    504:
    FDEH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    SMR:
    MIM:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human SHMT
    ELISA Kit for Human SHMT
    ELISA Kit for Human SHMT
    CLIA Kit for Human SHMT
    CLIA Kit for Human SHMT
    CLIA Kit for Human SHMT
    Polyclonal Antibody for Human SHMT
    Polyclonal Antibody for Human SHMT
    Polyclonal Antibody for Human SHMT
    Monoclonal Antibody for Human SHMT
    Monoclonal Antibody for Human SHMT
    Monoclonal Antibody for Human SHMT
    Protein for Human SHMT
    Protein for Human SHMT
    Protein for Human SHMT

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
    2. 2.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    3. 3.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Lymph.
      tissue: Muscle.
      tissue: Ovary.
      tissue: Uterus.
    6. 6.
      "The genetic organization and protein crystallographic structure of human serine hydroxymethyltransferase."
      Snell K. , Baumann U. , Byrne P.C. , Chave K.J. , Renwick S.B. , Sanders P.G. , Whitehouse S.K.
      Adv. Enzyme Regul.40:353-403(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-35
    7. 7.
      "Molecular cloning, characterization, and regulation of the human mitochondrial serine hydroxymethyltransferase gene."
      Stover P.J. , Chen L.H. , Suh J.R. , Stover D.M. , Keyomarsi K. , Shane B.
      J. Biol. Chem.272:1842-1848(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 22-504
    8. 8.
      "Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization."
      Garrow T.A. , Brenner A.A. , Whitehead M.V. , Chen X.-N. , Duncan R.G. , Korenberg J.R. , Shane B.
      J. Biol. Chem.268:11910-11916(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 31-504 (ISOFORM 1)
    9. 9.
      "The layered structure of human mitochondrial DNA nucleoids."
      Bogenhagen D.F. , Rousseau D. , Burke S.
      J. Biol. Chem.283:3665-3675(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;ASSOCIATION WITH MITOCHONDRIAL DNA;IDENTIFICATION BY MASS SPECTROMETRY
    10. 10.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-103; LYS-181; LYS-196; LYS-297; LYS-356; LYS-464; LYS-469 AND LYS-474;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      "Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria."
      Anderson D.D. , Quintero C.M. , Stover P.J.
      Proc. Natl. Acad. Sci. U.S.A.108:15163-15168(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    13. 13.
      "Crystal structure of human mitochondrial serine hydroxymethyltransferase 2."
      Structural genomics consortium (SGC)
      Submitted (2010-10) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.04 ANGSTROMS) OF 17-504
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