Gene name:
GMEB2 (KIAA1269) ;
Protein name:
Glucocorticoid modulatory element-binding protein 2 (GMEB-2) ;
Alternative:
Parvovirus initiation factor p79 (PIF p79) ;DNA-binding protein p79PIF ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer, and heterodimer of GMEB1 and GMEB2. GMEB1 and GMEB2 form the parvovirus initiator complex (PIF). Interacts with the glucocorticoid receptor (NR3C1). May interact with CREB-binding protein (CBP).
Function:
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.
Subcellular Location:
Nucleus
Cytoplasm
May be also cytoplasmic.
Protein Attributes:
50:
MATPDVSVHM | EEVVVVTTPD | TAVDGSGVEG | VKTVLVTTNL | APHGGDLTED |
100:
NMETENAAAA | AAAAFTASSQ | LKEAVLVKMA | EEGENLEAEI | VYPITCGDSR |
150:
ANLIWRKFVC | PGINVKCVQY | DEHVISPKEF | VHLAGKSTLK | DWKRAIRMNG |
200:
IMLRKIMDSG | ELDFYQHDKV | CSNTCRSTKI | DLSGARVSLS | SPTSAEYIPL |
250:
TPAAADVNGS | PATITIETCE | DPGDWTAAIG | DDTFTFWRGL | KDAGLLDEVI |
300:
QEFHQELVET | MRGLQQRVQD | PPLQLRDAVL | LNNIVQNFGM | LDLVKKVLAS |
350:
HKCQMDRSRE | QYARDLAALE | QQCDEHRRRA | KELKHKSQHL | SNVLMTLTPV |
400:
SLPPPVKRPR | LARATSGPAA | MASQVLTQSA | QLALGPGVPV | PQLTSVPLGK |
450:
VVSTLPSTVL | GKGSLQAPPA | SSPASPLLGG | YTVLASSGST | YPSTVEIHPD |
500:
ASSLTVLSTA | AVQDGSTVFK | VVSPLQLLTL | PGLGPTLQNV | AQASPGSSTI |
530:
VTVPAGAAPG | PEEHTATIEV | AAMAEDHERK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Human GMEB-2
ELISA Kit for Human GMEB-2
ELISA Kit for Human GMEB-2
CLIA Kit for Human GMEB-2
CLIA Kit for Human GMEB-2
CLIA Kit for Human GMEB-2
Polyclonal Antibody for Human GMEB-2
Polyclonal Antibody for Human GMEB-2
Polyclonal Antibody for Human GMEB-2
Monoclonal Antibody for Human GMEB-2
Monoclonal Antibody for Human GMEB-2
Monoclonal Antibody for Human GMEB-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 156-169
tissue :
Cervix carcinoma .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-373;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Leukemic T-cell .