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Index > Protein center > GMEB2(Gene name) > Human
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  • GMEB2 (Gene name),
  • Glucocorticoid modulatory element-binding protein 2 (Protein name ),  GMEB2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GMEB2(KIAA1269);
    Protein name:
    Glucocorticoid modulatory element-binding protein 2(GMEB-2);
    Alternative:
    Parvovirus initiation factor p79(PIF p79);DNA-binding protein p79PIF;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer, and heterodimer of GMEB1 and GMEB2. GMEB1 and GMEB2 form the parvovirus initiator complex (PIF). Interacts with the glucocorticoid receptor (NR3C1). May interact with CREB-binding protein (CBP).
    Function:
    Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.
    Subcellular Location:
    Nucleus Cytoplasm May be also cytoplasmic.
    Protein Attributes:
    Sequence length:
    530
    Sequence:
    50:
    MATPDVSVHM | EEVVVVTTPD | TAVDGSGVEG | VKTVLVTTNL | APHGGDLTED | 
    100:
    NMETENAAAA | AAAAFTASSQ | LKEAVLVKMA | EEGENLEAEI | VYPITCGDSR | 
    150:
    ANLIWRKFVC | PGINVKCVQY | DEHVISPKEF | VHLAGKSTLK | DWKRAIRMNG | 
    200:
    IMLRKIMDSG | ELDFYQHDKV | CSNTCRSTKI | DLSGARVSLS | SPTSAEYIPL | 
    250:
    TPAAADVNGS | PATITIETCE | DPGDWTAAIG | DDTFTFWRGL | KDAGLLDEVI | 
    300:
    QEFHQELVET | MRGLQQRVQD | PPLQLRDAVL | LNNIVQNFGM | LDLVKKVLAS | 
    350:
    HKCQMDRSRE | QYARDLAALE | QQCDEHRRRA | KELKHKSQHL | SNVLMTLTPV | 
    400:
    SLPPPVKRPR | LARATSGPAA | MASQVLTQSA | QLALGPGVPV | PQLTSVPLGK | 
    450:
    VVSTLPSTVL | GKGSLQAPPA | SSPASPLLGG | YTVLASSGST | YPSTVEIHPD | 
    500:
    ASSLTVLSTA | AVQDGSTVFK | VVSPLQLLTL | PGLGPTLQNV | AQASPGSSTI | 
    530:
    VTVPAGAAPG | PEEHTATIEV | AAMAEDHERK | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    MIM:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human GMEB-2
    ELISA Kit for Human GMEB-2
    ELISA Kit for Human GMEB-2
    CLIA Kit for Human GMEB-2
    CLIA Kit for Human GMEB-2
    CLIA Kit for Human GMEB-2
    Polyclonal Antibody for Human GMEB-2
    Polyclonal Antibody for Human GMEB-2
    Polyclonal Antibody for Human GMEB-2
    Monoclonal Antibody for Human GMEB-2
    Monoclonal Antibody for Human GMEB-2
    Monoclonal Antibody for Human GMEB-2
    Protein for Human GMEB-2
    Protein for Human GMEB-2
    Protein for Human GMEB-2

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    Precision
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    Linearity
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    References
    1. 1.
      "Two new members of the emerging KDWK family of combinatorial transcription modulators bind as a heterodimer to flexibly spaced PuCGPy half-sites."
      Christensen J. , Cotmore S.F. , Tattersall P.
      Mol. Cell. Biol.19:7741-7750(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 156-169
      tissue: Cervix carcinoma.
    2. 2.
      "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Ishikawa K. , Kikuno R. , Hirosawa M. , Nomura N. , Ohara O.
      DNA Res.6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    3. 3.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 24-530
      tissue: Testis.
    7. 7.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-373;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
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