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Index > Protein center > GNA11(Gene name) > Human
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  • GNA11 (Gene name),
  • Guanine nucleotide-binding protein subunit alpha-11 (Protein name ),  GNA11_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GNA11(GA11);
    Protein name:
    Guanine nucleotide-binding protein subunit alpha-11(G alpha-11;G-protein subunit alpha-11);
    Alternative:
    Guanine nucleotide-binding protein G(y) subunit alpha;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
    Function:
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.
    Subcellular Location:
    Cell membrane Lipid-anchor
    Protein Attributes:
    Sequence length:
    359
    Sequence:
    50:
    MTLESMMACC | LSDEVKESKR | INAEIEKQLR | RDKRDARREL | KLLLLGTGES | 
    100:
    GKSTFIKQMR | IIHGAGYSEE | DKRGFTKLVY | QNIFTAMQAM | IRAMETLKIL | 
    150:
    YKYEQNKANA | LLIREVDVEK | VTTFEHQYVS | AIKTLWEDPG | IQECYDRRRE | 
    200:
    YQLSDSAKYY | LTDVDRIATL | GYLPTQQDVL | RVRVPTTGII | EYPFDLENII | 
    250:
    FRMVDVGGQR | SERRKWIHCF | ENVTSIMFLV | ALSEYDQVLV | ESDNENRMEE | 
    300:
    SKALFRTIIT | YPWFQNSSVI | LFLNKKDLLE | DKILYSHLVD | YFPEFDGPQR | 
    350:
    DAQAAREFIL | KMFVDLNPDS | DKIIYSHFTC | ATDTENIRFV | FAAVKDTILQ | 
    359:
    LNLKEYNLV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    Pfam:
    UniGene:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human G alpha-11
    ELISA Kit for Human G alpha-11
    ELISA Kit for Human G alpha-11
    ELISA Kit for Human G alpha-11
    ELISA Kit for Human G alpha-11
    ELISA Kit for Human G alpha-11
    CLIA Kit for Human G alpha-11
    CLIA Kit for Human G alpha-11
    CLIA Kit for Human G alpha-11
    CLIA Kit for Human G alpha-11
    CLIA Kit for Human G alpha-11
    CLIA Kit for Human G alpha-11
    Polyclonal Antibody for Human G alpha-11
    Polyclonal Antibody for Human G alpha-11
    Polyclonal Antibody for Human G alpha-11
    Polyclonal Antibody for Human G alpha-11
    Polyclonal Antibody for Human G alpha-11
    Polyclonal Antibody for Human G alpha-11
    Monoclonal Antibody for Human G alpha-11
    Monoclonal Antibody for Human G alpha-11
    Monoclonal Antibody for Human G alpha-11
    Monoclonal Antibody for Human G alpha-11
    Monoclonal Antibody for Human G alpha-11
    Monoclonal Antibody for Human G alpha-11
    Protein for Human G alpha-11
    Protein for Human G alpha-11
    Protein for Human G alpha-11
    Protein for Human G alpha-11
    Protein for Human G alpha-11
    Protein for Human G alpha-11

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells."
      Jiang M. , Pandey S. , Tran V.T. , Fong H.K.W.
      Proc. Natl. Acad. Sci. U.S.A.88:3907-3911(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Retina.
    2. 2.
      Bai X.H. , Acharya R. , Bai Y.H. , Murtagh J.J.
      Submitted (1997-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
      Puhl H.L. III , Ikeda S.R. , Aronstam R.S.
      Submitted (2002-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Pancreas.
    7. 7.
      Bienvenut W.V. , Calvo F. , Kolch W.
      Submitted (2008-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 42-52 AND 159-166;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Cervix carcinoma.
    8. 8.
      "Ca2+ signalling in K562 human erythroleukaemia cells: effect of dimethyl sulphoxide and role of G-proteins in thrombin- and thromboxane A2-activated pathways."
      Thomas C.P. , Dunn M.J. , Mattera R.
      Biochem. J.312:151-158(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 244-337
      tissue: Hematopoietic.
    9. 9.
      "RGS22, a novel testis-specific regulator of G-protein signaling involved in human and mouse spermiogenesis along with GNA12/13 subunits."
      Hu Y. , Xing J. , Chen L. , Guo X. , Du Y. , Zhao C. , Zhu Y. , Lin M. , Zhou Z. , Sha J.
      Biol. Reprod.79:1021-1029(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGS22;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      tissue: Testis.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      "Neurotensin receptor-1 inducible palmitoylation is required for efficient receptor-mediated mitogenic-signaling within structured membrane microdomains."
      Heakal Y. , Woll M.P. , Fox T. , Seaton K. , Levenson R. , Kester M.
      Cancer Biol. Ther.12:427-435(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NTSR1
    12. 12.
      "Site-specific analysis of protein S-acylation by resin-assisted capture."
      Forrester M.T. , Hess D.T. , Thompson J.W. , Hultman R. , Moseley M.A. , Stamler J.S. , Casey P.J.
      J. Lipid Res.52:393-398(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION AT CYS-9 AND CYS-10
    13. 13.
      "A rude awakening--the perioperative sleep apnea epidemic."
      Memtsoudis S.G. , Besculides M.C. , Mazumdar M.
      N. Engl. J. Med.368:2352-2353(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HYPOC2 CYS-60 AND TRP-211
    14. 14.
      "Mutations affecting G-protein subunit alpha11 in hypercalcemia and hypocalcemia."
      Nesbit M.A. , Hannan F.M. , Howles S.A. , Babinsky V.N. , Head R.A. , Cranston T. , Rust N. , Hobbs M.R. , Heath H. III , Thakker R.V.
      N. Engl. J. Med.368:2476-2486(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HHC2 GLN-135 AND ILE-200 DEL;VARIANTS HYPOC2 GLN-181 AND LEU-341;CHARACTERIZATION OF VARIANTS HHC2 GLN-135 AND ILE-200 DEL;CHARACTERIZATION OF VARIANTS HYPOC2 GLN-181 AND LEU-341
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