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Index > Protein center > GNAI1(Gene name) > Bovine
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  • GNAI1 (Gene name),
  • Guanine nucleotide-binding protein G(i) subunit alpha-1 (Protein name ),  GNAI1_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    GNAI1;
    Protein name:
    Guanine nucleotide-binding protein G(i) subunit alpha-1;
    Alternative:
    Adenylate cyclase-inhibiting G alpha protein;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with RGS12. Interacts (via active GTP- or inactive GDP-bound forms) with RGS14 (via RGS and GoLoco domains); the interaction occurs in the centrosomes. Interacts (GDP-bound form) with RIC8A (via C-terminus). Interacts with DRD2. Interacts with GPSM1.
    Function:
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.
    Subcellular Location:
    Nucleus Cytoplasm Cell membrane Cytoplasm cytoskeleton centrosome Localizes in the centrosomes of interphase and mitotic cells, but not in centrosomes during cytokinesis. Detected at the cleavage furrow or the midbody. Localized at the plasma membrane throughout mitosis. Colocalizes with RIC8A and RGS14 at the plasma membrane.
    Protein Attributes:
    Sequence length:
    354
    Sequence:
    50:
    MGCTLSAEDK | AAVERSKMID | RNLREDGEKA | AREVKLLLLG | AGESGKSTIV | 
    100:
    KQMKIIHEAG | YSEEECKQYK | AVVYSNTIQS | IIAIIRAMGR | LKIDFGDSAR | 
    150:
    ADDARQLFVL | AGAAEEGFMT | AELAGVIKRL | WKDSGVQACF | NRSREYQLND | 
    200:
    SAAYYLNDLD | RIAQPNYIPT | QQDVLRTRVK | TTGIVETHFT | FKDLHFKMFD | 
    250:
    VGGQRSERKK | WIHCFEGVTA | IIFCVALSDY | DLVLAEDEEM | NRMHESMKLF | 
    300:
    DSICNNKWFT | DTSIILFLNK | KDLFEEKIKK | SPLTICYPEY | AGSNTYEEAA | 
    350:
    AYIQCQFEDL | NKRKDTKEIY | THFTCATDTK | NVQFVFDAVT | DVIIKNNLKD | 
    354:
    CGLF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Cat.:
    E16381r
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    Packing:
    96T
    ELISA Kit for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Cat.:
    E16381h
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    Packing:
    96T
    ELISA Kit for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Cat.:
    E16381m
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    Packing:
    96T
    ELISA Kit for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Cat.:
    E16381c
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    Packing:
    96T
    ELISA Kit for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Cat.:
    E16381b
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    Packing:
    96T
    CLIA Kit for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Cat.:
    U16381h
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Cat.:
    U16381r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Cat.:
    U16381b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Cat.:
    U16381c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Cat.:
    U16381m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Cat.:
    P16381Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Polyclonal Antibody for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Cat.:
    P16381Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Cat.:
    P16381Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Monoclonal Antibody for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Monoclonal Antibody for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Monoclonal Antibody for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Monoclonal Antibody for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Monoclonal Antibody for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Protein for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Protein for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Protein for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Protein for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1
    Protein for Bovine Guanine nucleotide-binding protein G(i) subunit alpha-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Primary structure of the alpha-subunit of bovine adenylate cyclase-inhibiting G-protein deduced from the cDNA sequence."
      Nukada T. , Tanabe T. , Takahashi H. , Noda M. , Haga K. , Haga T. , Ichiyama A. , Kangawa K. , Hiranaga M. , Matsuo H. , Numa S.
      FEBS Lett.197:305-310(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Hypothalamus.
    3. 3.
      "Molecular cloning and characterization of cDNA encoding the GTP-binding protein alpha i and identification of a related protein, alpha h."
      Michel T. , Winslow J.W. , Smith J.A. , Seidman J.G. , Neer E.J.
      Proc. Natl. Acad. Sci. U.S.A.83:7663-7667(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 106-354
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