Gnai2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comGnai2 ELISA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Gnai2(Gene name) > Rat

Gnai2 (Gene name),

Guanine nucleotide-binding protein G(i) subunit alpha-2 (Protein name ), GNAI2_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Gnai2(Gnai-2);

Protein name:

Guanine nucleotide-binding protein G(i) subunit alpha-2;

Alternative:

Adenylate cyclase-inhibiting G alpha protein;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UNC5B (By similarity). Interacts with GPSM1. Interacts with RGS12 and RGS14.

Function:

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division.

Subcellular Location:

Cytoplasm Cell membrane Cytoplasm cytoskeleton centrosome Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody.

Protein Attributes:

Sequence length:

355

Sequence:

50:

100:

150:

200:

250:

300:

350:

355:

DCGLF

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

String:

P04897

Pfam:

PF00503

KEGG:

rno:81664

UniGene:

Rn.3036

SMR:

P04897

Uniprot:

P04897

FOR

ELISA Kit for Rat Guanine nucleotide-binding protein G(i) subunit alpha-2

CLIA Kit for Rat Guanine nucleotide-binding protein G(i) subunit alpha-2

Polyclonal Antibody for Rat Guanine nucleotide-binding protein G(i) subunit alpha-2

Monoclonal Antibody for Rat Guanine nucleotide-binding protein G(i) subunit alpha-2

Protein for Rat Guanine nucleotide-binding protein G(i) subunit alpha-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain."
Itoh H. , Kozasa T. , Nagata S. , Nakamura S. , Katada T. , Ui M. , Iwai S. , Ohtsuka E. , Kawasaki H. , Suzuki K. , Kaziro Y.
Proc. Natl. Acad. Sci. U.S.A.83:3776-3780(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium."
Jones D.T. , Reed R.R.
J. Biol. Chem.262:14241-14249(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
4.

"Purification and characterization of Go alpha and three types of Gi alpha after expression in Escherichia coli."
Linder M.E. , Ewald D.A. , Miller R.J. , Gilman A.G.
J. Biol. Chem.265:8243-8251(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 12-126
5.

"Activator of G protein signaling 3 is a guanine dissociation inhibitor for Galpha i subunits."
de Vries L. , Fischer T. , Tronchere H. , Brothers G.M. , Strockbine B. , Siderovski D.P. , Farquhar M.G.
Proc. Natl. Acad. Sci. U.S.A.97:14364-14369(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GPSM1
6.

"RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity."
Kimple R.J. , De Vries L. , Tronchere H. , Behe C.I. , Morris R.A. , Gist Farquhar M. , Siderovski D.P.
J. Biol. Chem.276:29275-29281(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGS12 AND RGS14
7.

"Selective interactions between Gi alpha1 and Gi alpha3 and the GoLoco/GPR domain of RGS14 influence its dynamic subcellular localization."
Shu F.J. , Ramineni S. , Amyot W. , Hepler J.R.
Cell. Signal.19:163-176(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
8.

"The RGS14 GoLoco domain discriminates among Galphai isoforms."
Mittal V. , Linder M.E.
J. Biol. Chem.279:46772-46778(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF MET-82; VAL-85; LYS-86; ASN-90; GLN-92; ALA-96; PRO-98; GLN-99; SER-111; CYS-112; PRO-121 AND GLU-122
9.

"Localization of Gi alpha proteins in the centrosomes and at the midbody: implication for their role in cell division."
Cho H. , Kehrl J.H.
J. Cell Biol.178:245-255(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION

Product Feedback Wall

* Email:
*Comments: