Gnas ELISA Kit for Mouse(Mus musculus) | EIAab.comGnas ELISA Kit for Mouse(Mus musculus)

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Gnas (Gene name),

Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Protein name ), GNAS1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Gnas(Gnas1);

Protein name:

Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas;

Alternative:

Extra large alphas protein(XLalphas);Adenylate cyclase-stimulating G alpha protein;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts through its N-terminal region with ALEX which is produced from the same locus in a different open reading frame. This interaction may inhibit its adenylyl cyclase-stimulating activity.

Function:

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms.

Subcellular Location:

Cell membrane Peripheral membrane protein

Protein Attributes:

Sequence length:

1133

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1133:

HFTCAVDTEN | IRRVFNDCRD | IIQRMHLRQY | ELL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.125770

SMR:

Q6R0H7

Pfam:

PF00503

String:

Q6R0H7

KEGG:

mmu:14683

Uniprot:

Q6R0H7

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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E14288m

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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E14288r

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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E14288m

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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E14288m

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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E14288d

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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E14288b

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ELISA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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U14288m

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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U14288d

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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U14288r

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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U14288p

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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U14288r

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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U14288m

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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U14288b

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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U14288r

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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CLIA Kit for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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Polyclonal Antibody for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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P14288Rb-h

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Polyclonal Antibody for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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P14288Rb-m

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Polyclonal Antibody for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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P14288Rb-r

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Polyclonal Antibody for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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P14288Rb-r

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Polyclonal Antibody for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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P14288Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

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P14288Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

Cat.:

P14288Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

Cat.:

P14288Rb-h

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Packing:

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Monoclonal Antibody for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

Protein for Mouse Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"XL alpha-s, the extra-long form of the alpha subunit of the Gs G protein, is significantly longer than suspected, and so is its companion Alex."
Abramowitz J. , Grenet D. , Birnbaumer M. , Torres H.N. , Birnbaumer L.
Proc. Natl. Acad. Sci. U.S.A.101:8366-8371(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS XLAS-1; XLAS-2 AND XLAS-3);NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 935-1018 (ISOFORM XLAS-1)
strain: 129/Sv.
strain: BALB/c.
strain: C57BL/6J.
strain: FVB/N.
tissue: Brain.
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

"An imprinted antisense transcript at the human GNAS1 locus."
Hayward B.E. , Bonthron D.T.
Hum. Mol. Genet.9:835-841(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-785
4.

"Characterization of the extra-large G protein alpha-subunit XLalphas. II. Signal transduction properties."
Klemke M. , Pasolli H.A. , Kehlenbach R.H. , Offermanns S. , Schultz G. , Huttner W.B.
J. Biol. Chem.275:33633-33640(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 357-1133 (ISOFORM XLAS-4)
strain: C57BL/6.
5.

"Receptor-mediated adenylyl cyclase activation through XLalpha(s), the extra-large variant of the stimulatory G protein alpha-subunit."
Bastepe M. , Gunes Y. , Perez-Villamil B. , Hunzelman J. , Weinstein L.S. , Jueppner H.
Mol. Endocrinol.16:1912-1919(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE

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