GNLY ELISA Kit for Human(Homo sapiens) | EIAab.comGNLY ELISA Kit for Human(Homo sapiens)

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Index > Protein center > GNLY(Gene name) > Human

GNLY (Gene name),

Granulysin (Protein name ), GNLY_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

GNLY(LAG2;NKG5;TLA519);

Protein name:

Granulysin;

Alternative:

Protein NKG5;Lymphokine LAG-2;T-cell activation protein 519;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Function:

Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.

Subcellular Location:

Secreted Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation.

Protein Attributes:

Sequence length:

145

Sequence:

50:

100:

145:

SRWRDVCRNF | MRRYQSRVTQ | GLVAGETAQQ | ICEDLRLCIP | STGPL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:10578

UniGene:

Hs.105806

SMR:

P22749

MIM:

188855

String:

P22749

Pfam:

PF03489

STRING:

9606.ENSP00000263863

Uniprot:

P22749

FOR

ELISA Kit for Human Granulysin

Cat.:

E1517h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Granulysin

Cat.:

U1517h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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Polyclonal Antibody for Human Granulysin

Cat.:

P1517Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Granulysin

Protein for Human Granulysin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Halleck A. , Ebert L. , Mkoundinya M. , Schick M. , Eisenstein S. , Neubert P. , Kstrang K. , Schatten R. , Shen B. , Henze S. , Mar W. , Korn B. , Zuo D. , Hu Y. , LaBaer J.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: B-cell.
3.

"Granulysin: a novel antimicrobial peptide of cytolytic T lymphocytes and natural killer cells."
Krensky A.M.
Biochem. Pharmacol.59:317-320(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
4.

"An antimicrobial activity of cytolytic T cells mediated by granulysin."
Stenger S. , Hanson D.A. , Teitelbaum R. , Dewan P. , Niazi K.R. , Froelich C.J. , Ganz T. , Thoma-Uszynski S. , Melian A. , Bogdan C. , Porcelli S.A. , Bloom B.R. , Krensky A.M. , Modlin R.L.
Science282:121-125(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
5.

"Biosynthesis of granulysin, a novel cytolytic molecule."
Hanson D.A. , Kaspar A.A. , Poulain F.R. , Krensky A.M.
Mol. Immunol.36:413-422(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING
6.

"Granulysin crystal structure and a structure-derived lytic mechanism."
Anderson D.H. , Sawaya M.R. , Cascio D. , Ernst W. , Modlin R. , Krensky A. , Eisenberg D.
J. Mol. Biol.325:355-365(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (0.92 ANGSTROMS) OF 63-136
7.

"The isolation and sequence of a novel gene from a human functional T cell line."
Jongstra J. , Schall T.J. , Dyer B.J. , Clayberger C. , Jorgensen J. , Davis M.M. , Krensky A.M.
J. Exp. Med.165:601-614(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT);VARIANT ILE-119
8.

"A cDNA clone expressed in natural killer and T cells that likely encodes a secreted protein."
Yabe T. , McSherry C. , Bach F.H. , Houchins J.P.
J. Exp. Med.172:1159-1163(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG)
9.

"Genomic structure of NKG5, a human NK and T cell-specific activation gene."
Houchins J.P. , Kricek F. , Chujor C.S. , Heise C.P. , Yabe T. , McSherry C. , Bach F.H.
Immunogenetics37:102-107(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ILE-119
tissue: Placenta.

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