Protein name:
Granzyme M ;
Alternative:
Natural killer cell granular protease ;Met-ase ;RNK-Met-1 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
Subcellular Location:
Secreted
Cytoplasmic granule
Granules of large granular lymphocytes.
Protein Attributes:
50:
LLLLLALKTL | WAVGNRFEAQ | IIGGREAVPH | SRPYMVSLQN | TKSHMCGGVL |
100:
VHQKWVLTAA | HCLSEPLQQL | KLVFGLHSLH | DPQDPGLTFY | IKQAIKHPGY |
150:
NLKYENDLAL | LKLDGRVKPS | KNVKPLALPR | KPRDKPAEGS | RCSTAGWGIT |
200:
HQRGQLAKSL | QELDLRLLDT | RMCNNSRFWN | GVLTDSMLCL | KAGAKGQAPC |
250:
KGDSGGPLVC | GKGKVDGILS | FSSKNCTDIF | KPTVATAVAP | YSSWIRKVIG |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
ELISA Kit for Rat Granzyme M
ELISA Kit for Rat Granzyme M
CLIA Kit for Rat Granzyme M
CLIA Kit for Rat Granzyme M
Polyclonal Antibody for Rat Granzyme M
Polyclonal Antibody for Rat Granzyme M
Monoclonal Antibody for Rat Granzyme M
Monoclonal Antibody for Rat Granzyme M
Protein for Rat Granzyme M
Protein for Rat Granzyme M
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Purification and cloning of a novel serine protease, RNK-Met-1, from the granules of a rat natural killer cell leukemia."
Smyth M.J.
,
Wiltrout T.
,
Trapani J.A.
,
Ottaway K.S.
,
Sowder R.
,
Henderson L.E.
,
Kam C.-M.
,
Powers J.C.
,
Young H.A.
,
Sayers T.J.
J. Biol. Chem.267:24418-24425(1992)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 21-44
Vaild Sequence:
