Protein name:
GRB2-related adapter protein ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Associates through its SH2 domain with ligand-activated receptors for stem cell factor (KIT) and erythropoietin (EPOR). Also forms a stable complex with the Bcr-Abl oncoprotein. GRAP is associated with the Ras guanine nucleotide exchange factor SOS1, primarily through its N-terminal SH3 domain. Interacts with phosphorylated LAT upon TCR activation. Interacts with SHB.
Function:
Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
Subcellular Location:
N/A
Protein Attributes:
50:
MESVALYSFQ | ATESDELAFN | KGDTLKILNM | EDDQNWYKAE | LRGVEGFIPK |
100:
NYIRVKPHPW | YSGRISRQLA | EEILMKRNHL | GAFLIRESES | SPGEFSVSVN |
150:
YGDQVQHFKV | LREASGKYFL | WEEKFNSLNE | LVDFYRTTTI | AKKRQIFLRD |
200:
EEPLLKSPGA | CFAQAQFDFS | AQDPSQLSFR | RGDIIEVLER | PDPHWWRGRS |
217:
CGRVGFFPRS | YVQPVHL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Bovine
Human
ELISA Kit for Human GRB2-related adapter protein
ELISA Kit for Human GRB2-related adapter protein
ELISA Kit for Human GRB2-related adapter protein
CLIA Kit for Human GRB2-related adapter protein
CLIA Kit for Human GRB2-related adapter protein
CLIA Kit for Human GRB2-related adapter protein
Polyclonal Antibody for Human GRB2-related adapter protein
Polyclonal Antibody for Human GRB2-related adapter protein
Polyclonal Antibody for Human GRB2-related adapter protein
Monoclonal Antibody for Human GRB2-related adapter protein
Monoclonal Antibody for Human GRB2-related adapter protein
Monoclonal Antibody for Human GRB2-related adapter protein
Protein for Human GRB2-related adapter protein
Protein for Human GRB2-related adapter protein
Protein for Human GRB2-related adapter protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
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more...
Nature440:1045-1049(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Blood .
tissue :
Brain .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH LAT
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SHB