Protein name:
Glutamate receptor-interacting protein 1 (GRIP-1) ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with EPHA7, EPHB2, KIF5A, KIF5B, KIF5C, GRIA2, GRIA3, GRIPAP1/GRASP1, PPFIA1, PPFIA4, FRAS1, PLCD4, PTPRF and liprins-alpha. Can form homomultimers or heteromultimers with GRIP2. Forms a ternary complex with GRIA2 and CSPG4 (By similarity). Interacts with EFNB1, EFNB3 and the C-terminal tail of PRLHR. Interacts with SLC30A9.
Function:
May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.
Subcellular Location:
Cytoplasmic vesicle
Endoplasmic reticulum
Cell junction
synapse
postsynaptic cell membrane
Cytoplasmic and membrane-associated with vesicles, peri-Golgi complexes and endoplasmic reticulum. Enriched in post-synaptic plasma membrane and post-synaptic densities.
Protein Attributes:
50:
MIAVSFKCRC | QILRRLTKDE | SPYTKSASQT | KPPDGALAVR | RQSIPEEFKG |
100:
STVVELMKKE | GTTLGLTVSG | GIDKDGKPRV | SNLRQGGIAA | RSDQLDVGDY |
150:
IKAVNGINLA | KFRHDEIISL | LKNVGERVVL | EVEYELPPVS | VQGSSVIFRT |
200:
VEVTLHKEGN | TFGFVIRGGA | HDDRNKSRPV | VITCVRPGGP | ADREGTIKPG |
250:
DRLLSVDGIR | LLGTTHAEAM | SILKQCGQEA | ALLIEYDVSV | MDSVATASGP |
300:
LLVEVAKTPG | ASLGVALTTS | MCCNKQVIVI | DKIKSASIAD | RCGALHVGDH |
350:
ILSIDGTSME | YCTLAEATQF | LANTTDQVKL | EILPHHQTRL | ALKGPDHVKI |
400:
QRSDRQLTWD | SWASNHSSLH | TNHHYNTYHP | DHCRVPALTF | PKAPPPNSPP |
450:
ALVSSSFSPT | SMSAYSLSSL | NMGTLPRSLY | STSPRGTMMR | RRLKKKDFKS |
500:
SLSLASSTVG | LAGQVVHTET | TEVVLTADPV | TGFGIQLQGS | VFATETLSSP |
550:
PLISYIEADS | PAERCGVLQI | GDRVMAINGI | PTEDSTFEEA | SQLLRDSSIT |
600:
SKVTLEIEFD | VAESVIPSSG | TFHVKLPKKH | NVELGITISS | PSSRKPGDPL |
650:
VISDIKKGSV | AHRTGTLELG | DKLLAIDNIR | LDNCSMEDAV | QILQQCEDLV |
700:
KLKIRKDEDN | SDEQESSGAI | IYTVELKRYG | GPLGITISGT | EEPFDPIIIS |
750:
SLTKGGLAER | TGAIHIGDRI | LAINSSSLKG | KPLSEAIHLL | QMAGETVTLK |
800:
IKKQTDAQSA | SSPKKFPISS | HLSDLGDVEE | DSSPAQKPGK | LSDMYPSTVP |
850:
SVDSAVDSWD | GSAIDTSYGT | QGTSFQASGY | NFNTYDWRSP | KQRGSLSPVT |
900:
KPRSQTYPDV | GLSYEDWDRS | TASGFAGAAD | SAETEQEENF | WSQALEDLET |
950:
CGQSGILREL | EEKADRRVSL | RNMTLLATIM | SGSTMSLNHE | APTPRSQLGR |
1000:
QASFQERSSS | RPHYSQTTRS | NTLPSDVGRK | SVTLRKMKQE | IKEIMSPTPV |
1050:
ELHKVTLYKD | SDMEDFGFSV | ADGLLEKGVY | VKNIRPAGPG | DLGGLKPYDR |
1100:
LLQVNHVRTR | DFDCCLVVPL | IAESGNKLDL | VISRNPLASQ | KSIDQQSLPG |
1128:
DWSEQNSAFF | QQPSHGGNLE | TREPTNTL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Human
ELISA Kit for Human GRIP-1
ELISA Kit for Human GRIP-1
ELISA Kit for Human GRIP-1
CLIA Kit for Human GRIP-1
CLIA Kit for Human GRIP-1
CLIA Kit for Human GRIP-1
Polyclonal Antibody for Human GRIP-1
Polyclonal Antibody for Human GRIP-1
Polyclonal Antibody for Human GRIP-1
Monoclonal Antibody for Human GRIP-1
Monoclonal Antibody for Human GRIP-1
Monoclonal Antibody for Human GRIP-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 265-1128 (ISOFORM 2);FUNCTION;INTERACTION WITH EFNB1 AND EFNB3;SUBCELLULAR LOCATION
tissue :
Fetal brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cited for : INTERACTION WITH WBSCR22