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Index > Protein center > GRIP1(Gene name) > Human
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  • GRIP1 (Gene name),
  • Glutamate receptor-interacting protein 1 (Protein name ),  GRIP1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    GRIP1;
    Protein name:
    Glutamate receptor-interacting protein 1(GRIP-1);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with EPHA7, EPHB2, KIF5A, KIF5B, KIF5C, GRIA2, GRIA3, GRIPAP1/GRASP1, PPFIA1, PPFIA4, FRAS1, PLCD4, PTPRF and liprins-alpha. Can form homomultimers or heteromultimers with GRIP2. Forms a ternary complex with GRIA2 and CSPG4 (By similarity). Interacts with EFNB1, EFNB3 and the C-terminal tail of PRLHR. Interacts with SLC30A9.
    Function:
    May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.
    Subcellular Location:
    Cytoplasmic vesicle Endoplasmic reticulum Cell junction synapse postsynaptic cell membrane Cytoplasmic and membrane-associated with vesicles, peri-Golgi complexes and endoplasmic reticulum. Enriched in post-synaptic plasma membrane and post-synaptic densities.
    Protein Attributes:
    Sequence length:
    1128
    Sequence:
    50:
    MIAVSFKCRC | QILRRLTKDE | SPYTKSASQT | KPPDGALAVR | RQSIPEEFKG | 
    100:
    STVVELMKKE | GTTLGLTVSG | GIDKDGKPRV | SNLRQGGIAA | RSDQLDVGDY | 
    150:
    IKAVNGINLA | KFRHDEIISL | LKNVGERVVL | EVEYELPPVS | VQGSSVIFRT | 
    200:
    VEVTLHKEGN | TFGFVIRGGA | HDDRNKSRPV | VITCVRPGGP | ADREGTIKPG | 
    250:
    DRLLSVDGIR | LLGTTHAEAM | SILKQCGQEA | ALLIEYDVSV | MDSVATASGP | 
    300:
    LLVEVAKTPG | ASLGVALTTS | MCCNKQVIVI | DKIKSASIAD | RCGALHVGDH | 
    350:
    ILSIDGTSME | YCTLAEATQF | LANTTDQVKL | EILPHHQTRL | ALKGPDHVKI | 
    400:
    QRSDRQLTWD | SWASNHSSLH | TNHHYNTYHP | DHCRVPALTF | PKAPPPNSPP | 
    450:
    ALVSSSFSPT | SMSAYSLSSL | NMGTLPRSLY | STSPRGTMMR | RRLKKKDFKS | 
    500:
    SLSLASSTVG | LAGQVVHTET | TEVVLTADPV | TGFGIQLQGS | VFATETLSSP | 
    550:
    PLISYIEADS | PAERCGVLQI | GDRVMAINGI | PTEDSTFEEA | SQLLRDSSIT | 
    600:
    SKVTLEIEFD | VAESVIPSSG | TFHVKLPKKH | NVELGITISS | PSSRKPGDPL | 
    650:
    VISDIKKGSV | AHRTGTLELG | DKLLAIDNIR | LDNCSMEDAV | QILQQCEDLV | 
    700:
    KLKIRKDEDN | SDEQESSGAI | IYTVELKRYG | GPLGITISGT | EEPFDPIIIS | 
    750:
    SLTKGGLAER | TGAIHIGDRI | LAINSSSLKG | KPLSEAIHLL | QMAGETVTLK | 
    800:
    IKKQTDAQSA | SSPKKFPISS | HLSDLGDVEE | DSSPAQKPGK | LSDMYPSTVP | 
    850:
    SVDSAVDSWD | GSAIDTSYGT | QGTSFQASGY | NFNTYDWRSP | KQRGSLSPVT | 
    900:
    KPRSQTYPDV | GLSYEDWDRS | TASGFAGAAD | SAETEQEENF | WSQALEDLET | 
    950:
    CGQSGILREL | EEKADRRVSL | RNMTLLATIM | SGSTMSLNHE | APTPRSQLGR | 
    1000:
    QASFQERSSS | RPHYSQTTRS | NTLPSDVGRK | SVTLRKMKQE | IKEIMSPTPV | 
    1050:
    ELHKVTLYKD | SDMEDFGFSV | ADGLLEKGVY | VKNIRPAGPG | DLGGLKPYDR | 
    1100:
    LLQVNHVRTR | DFDCCLVVPL | IAESGNKLDL | VISRNPLASQ | KSIDQQSLPG | 
    1128:
    DWSEQNSAFF | QQPSHGGNLE | TREPTNTL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    MIM:
    String:
    Pfam:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human GRIP-1
    ELISA Kit for Human GRIP-1
    ELISA Kit for Human GRIP-1
    CLIA Kit for Human GRIP-1
    CLIA Kit for Human GRIP-1
    CLIA Kit for Human GRIP-1
    Polyclonal Antibody for Human GRIP-1
    Polyclonal Antibody for Human GRIP-1
    Polyclonal Antibody for Human GRIP-1
    Monoclonal Antibody for Human GRIP-1
    Monoclonal Antibody for Human GRIP-1
    Monoclonal Antibody for Human GRIP-1
    Protein for Human GRIP-1
    Protein for Human GRIP-1
    Protein for Human GRIP-1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
    3. 3.
      "EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains."
      Brueckner K. , Pablo Labrador J. , Scheiffele P. , Herb A. , Seeburg P.H. , Klein R.
      Neuron22:511-524(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 265-1128 (ISOFORM 2);FUNCTION;INTERACTION WITH EFNB1 AND EFNB3;SUBCELLULAR LOCATION
      tissue: Fetal brain.
    4. 4.
      "The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering."
      Lin S.H.S. , Arai A.C. , Wang Z. , Nothacker H.-P. , Civelli O.
      Mol. Pharmacol.60:916-923(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PRLHR
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN FRASS
    6. 6.
      "The methyltransferase WBSCR22/Merm1 enhances glucocorticoid receptor function and is regulated in lung inflammation and cancer."
      Jangani M. , Poolman T.M. , Matthews L. , Yang N. , Farrow S.N. , Berry A. , Hanley N. , Williamson A.J. , Whetton A.D. , Donn R. , Ray D.W.
      J. Biol. Chem.289:8931-8946(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH WBSCR22
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