GRM2 ELISA Kit for Human(Homo sapiens) | EIAab.comGRM2 ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > GRM2(Gene name) > Human

GRM2 (Gene name),

Metabotropic glutamate receptor 2 (Protein name ), GRM2_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

GRM2(GPRC1B;MGLUR2);

Protein name:

Metabotropic glutamate receptor 2(mGluR2);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with GRASP.

Function:

Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

872

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

872:

GSQFVPTVCN | GREVVDSTTS | SL

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

String:

Q14416

KEGG:

hsa:2912

UniGene:

Hs.121510

MIM:

604099

STRING:

9606.ENSP00000378492

SMR:

Q14416

Pfam:

PF00003

Uniprot:

Q14416

FOR

ELISA Kit for Human mGluR2

CLIA Kit for Human mGluR2

Polyclonal Antibody for Human mGluR2

Monoclonal Antibody for Human mGluR2

Protein for Human mGluR2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning, functional expression and pharmacological characterization of the human metabotropic glutamate receptor type 2."
Flor P.J. , Lindauer K. , Puttner I. , Ruegg D. , Lukic S. , Knopfel T. , Kuhn R.
Eur. J. Neurosci.7:622-629(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
2.

"Structure and polymorphisms of the human metabotropic glutamate receptor type 2 (hmGluR2) gene: analysis of association with schizophrenia."
Yasuyuki F. , Akiko J.
Submitted (2000-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Complete coding sequence of human metabotropic glutamate receptor 2."
Bonner T.I. , Kauffman D. , Nagle J.W.
Submitted (2005-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
4.

Kaighin V.A. , Martin A.L. , Aronstam R.S.
Submitted (2007-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain cortex.
7.

"Identification of a serotonin/glutamate receptor complex implicated in psychosis."
Gonzalez-Maeso J. , Ang R.L. , Yuen T. , Chan P. , Weisstaub N.V. , Lopez-Gimenez J.F. , Zhou M. , Okawa Y. , Callado L.F. , Milligan G. , Gingrich J.A. , Filizola M. , Meana J.J. , Sealfon S.C.
Nature452:93-97(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTR2A;FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
8.

"Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A.mGlu2) receptor heteromerization and its psychoactive behavioral function."
Moreno J.L. , Muguruza C. , Umali A. , Mortillo S. , Holloway T. , Pilar-Cuellar F. , Mocci G. , Seto J. , Callado L.F. , Neve R.L. , Milligan G. , Sealfon S.C. , Lopez-Gimenez J.F. , Meana J.J. , Benson D.L. , Gonzalez-Maeso J.
J. Biol. Chem.287:44301-44319(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTR2A;FUNCTION;SUBCELLULAR LOCATION;MUTAGENESIS OF ALA-677; ALA-681 AND ALA-685
9.

"Heterocomplex formation of 5-HT2A-mGlu2 and its relevance for cellular signaling cascades."
Delille H.K. , Becker J.M. , Burkhardt S. , Bleher B. , Terstappen G.C. , Schmidt M. , Meyer A.H. , Unger L. , Marek G.J. , Mezler M.
Neuropharmacology62:2184-2191(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTR2A;FUNCTION;SUBCELLULAR LOCATION

Product Feedback Wall

* Email:
*Comments: