Gene name:
Grpel2 (Mt-grpel2) ;
Protein name:
GrpE protein homolog 2, mitochondrial ;
Alternative:
Mt-GrpE#2 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Probable component of the PAM complex at least composed of a mitochondrial HSP70 protein, GRPEL1 or GRPEL2, TIMM44, TIMM16/PAM16 and TIMM14/DNAJC19.
Function:
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
Subcellular Location:
Mitochondrion matrix
Protein Attributes:
50:
MAARSLWAVQ | RLQRLLASGA | MSESRGWLHP | FSTATQRTAG | EDCSSEDPPD |
100:
GLGPSLAEQA | LRLKAVKLEK | EVQDLTLRYQ | RAVADCENIR | RRTQRCVEDA |
150:
KIFGIQSFCK | DLVEVADILE | KTAKCCSEGA | EPEDHRRTLE | KVFQGLSLLE |
200:
ARLKSVFTKH | GLEKMTPIGD | KYDPHEHELI | CHMPAGVGVQ | PGTVALVRQD |
224:
GYKLHGRTIR | LAQVEVAVES | QRRL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
ELISA Kit for Mouse GrpE protein homolog 2, mitochondrial
ELISA Kit for Mouse GrpE protein homolog 2, mitochondrial
ELISA Kit for Mouse GrpE protein homolog 2, mitochondrial
CLIA Kit for Mouse GrpE protein homolog 2, mitochondrial
CLIA Kit for Mouse GrpE protein homolog 2, mitochondrial
CLIA Kit for Mouse GrpE protein homolog 2, mitochondrial
Polyclonal Antibody for Mouse GrpE protein homolog 2, mitochondrial
Polyclonal Antibody for Mouse GrpE protein homolog 2, mitochondrial
Polyclonal Antibody for Mouse GrpE protein homolog 2, mitochondrial
Monoclonal Antibody for Mouse GrpE protein homolog 2, mitochondrial
Monoclonal Antibody for Mouse GrpE protein homolog 2, mitochondrial
Monoclonal Antibody for Mouse GrpE protein homolog 2, mitochondrial
Protein for Mouse GrpE protein homolog 2, mitochondrial
Protein for Mouse GrpE protein homolog 2, mitochondrial
Protein for Mouse GrpE protein homolog 2, mitochondrial
R&D Technical Data
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Precision
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Recovery
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Linearity
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Brain .
tissue :
Embryo .
tissue :
Spinal cord .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 2-224