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Index > Protein center > GUCA1B(Gene name) > Human
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  • GUCA1B (Gene name),
  • Guanylyl cyclase-activating protein 2 (Protein name ),  GUC1B_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GUCA1B(GCAP2);
    Protein name:
    Guanylyl cyclase-activating protein 2(GCAP 2);
    Alternative:
    Guanylate cyclase activator 1B;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low, and GC1 and GC2 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.
    Subcellular Location:
    Cell membrane Membranes of outer segment.
    Protein Attributes:
    Sequence length:
    200
    Sequence:
    50:
    MGQEFSWEEA | EAAGEIDVAE | LQEWYKKFVM | ECPSGTLFMH | EFKRFFKVTD | 
    100:
    DEEASQYVEG | MFRAFDKNGD | NTIDFLEYVA | ALNLVLRGTL | EHKLKWTFKI | 
    150:
    YDKDGNGCID | RLELLNIVEG | IYQLKKACRR | ELQTEQGQLL | TPEEVVDRIF | 
    200:
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    MIM:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human GCAP 2
    ELISA Kit for Human GCAP 2
    ELISA Kit for Human GCAP 2
    ELISA Kit for Human GCAP 2
    CLIA Kit for Human GCAP 2
    CLIA Kit for Human GCAP 2
    CLIA Kit for Human GCAP 2
    CLIA Kit for Human GCAP 2
    Polyclonal Antibody for Human GCAP 2
    Polyclonal Antibody for Human GCAP 2
    Polyclonal Antibody for Human GCAP 2
    Polyclonal Antibody for Human GCAP 2
    Monoclonal Antibody for Human GCAP 2
    Monoclonal Antibody for Human GCAP 2
    Monoclonal Antibody for Human GCAP 2
    Monoclonal Antibody for Human GCAP 2
    Protein for Human GCAP 2
    Protein for Human GCAP 2
    Protein for Human GCAP 2
    Protein for Human GCAP 2

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    Precision
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    Linearity
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    References
    1. 1.
      "The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1)."
      Surguchov A. , Bronson J.D. , Banerjee P. , Knowles J.A. , Ruiz C. , Subbaraya I. , Palczewski K. , Baehr W.
      Genomics39:312-322(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "Genetic analysis of the guanylate cyclase activator 1B (GUCA1B) gene in patients with autosomal dominant retinal dystrophies."
      Payne A.M. , Downes S.M. , Bessant D.A.R. , Plant C. , Moore T. , Bird A.C. , Bhattacharya S.S.
      J. Med. Genet.36:691-693(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ASP-155
    4. 4.
      "Mutations in the gene coding for guanylate cyclase-activating protein 2 (GUCA1B gene) in patients with autosomal dominant retinal dystrophies."
      Sato M. , Nakazawa M. , Usui T. , Tanimoto N. , Abe H. , Ohguro H.
      Graefes Arch. Clin. Exp. Ophthalmol.243:235-242(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT RP48 ARG-157
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