Gulp1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comGulp1 ELISA Kit for Rat(Rattus norvegicus)

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Gulp1 (Gene name),

PTB domain-containing engulfment adapter protein 1 (Protein name ), GULP1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Gulp1(Ced6);

Protein name:

PTB domain-containing engulfment adapter protein 1;

Alternative:

PTB domain adapter protein CED-6;Cell death protein 6 homolog;Protein GULP;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer. Interacts with GDP-bound ARF6, but not with GTP-bound ARF6. Part of a complex composed of GULP1, ACAP1 and ARF6. Interacts with ACAP1, LRP1, MEGF10 and STAB2 (By similarity). Interacts with clathrin.

Function:

May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.

Subcellular Location:

Cytoplasm May associate with the cytoplasmic side of the plasma membrane and early endosomes (By similarity). Detected in synapses.

Protein Attributes:

Sequence length:

304

Sequence:

50:

100:

150:

200:

250:

300:

304:

DSRC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00640

KEGG:

rno:314543

String:

Q5PQS4

UniGene:

Rn.32649

Uniprot:

Q5PQS4

FOR

ELISA Kit for Rat PTB domain-containing engulfment adapter protein 1

CLIA Kit for Rat PTB domain-containing engulfment adapter protein 1

Polyclonal Antibody for Rat PTB domain-containing engulfment adapter protein 1

Monoclonal Antibody for Rat PTB domain-containing engulfment adapter protein 1

Protein for Rat PTB domain-containing engulfment adapter protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A rat homologue of CED-6 is expressed in neurons and interacts with clathrin."
Martins-Silva C. , Ferreira L.T. , Cyr M. , Koenen J. , Fernandes D.R. , Carvalho N.R. , Ribeiro C.B. , Marion S. , Chavez-Olortegui C. , Prado M.A. , Prado V.F.
Brain Res.1119:1-12(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);SUBCELLULAR LOCATION;INTERACTION WITH CLATHRIN;TISSUE SPECIFICITY
tissue: Brain.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Lung.

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