Protein name:
Hepatitis B virus X-interacting protein (HBV X-interacting protein;HBX-interacting protein) ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer (Probable). Interacts with phosphorylated BIRC5; the resulting complex binds pro-caspase-9, as well as active caspase-9, but much less efficiently. Interacts with SUPV3L1. Interacts with hepatitis B virus (HBV) oncoprotein HBX C-terminus.
Function:
When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MEATLEQHLE | DTMKNPSIVG | VLCTDSQGLN | LGCRGTLSDE | HAGVISVLAQ |
91:
QAAKLTSDPT | DIPVVCLESD | NGNIMIQKHD | GITVAVHKMA | S
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Bovine
Pig
ELISA Kit for Human HBV X-interacting protein
ELISA Kit for Human HBV X-interacting protein
ELISA Kit for Human HBV X-interacting protein
ELISA Kit for Human HBV X-interacting protein
CLIA Kit for Human HBV X-interacting protein
CLIA Kit for Human HBV X-interacting protein
CLIA Kit for Human HBV X-interacting protein
CLIA Kit for Human HBV X-interacting protein
Polyclonal Antibody for Human HBV X-interacting protein
Polyclonal Antibody for Human HBV X-interacting protein
Polyclonal Antibody for Human HBV X-interacting protein
Polyclonal Antibody for Human HBV X-interacting protein
Monoclonal Antibody for Human HBV X-interacting protein
Monoclonal Antibody for Human HBV X-interacting protein
Monoclonal Antibody for Human HBV X-interacting protein
Monoclonal Antibody for Human HBV X-interacting protein
Protein for Human HBV X-interacting protein
Protein for Human HBV X-interacting protein
Protein for Human HBV X-interacting protein
Protein for Human HBV X-interacting protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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