Gene name:
HECW2 (KIAA1301;NEDL2) ;
Protein name:
E3 ubiquitin-protein ligase HECW2 ;
Alternative:
NEDD4-like E3 ubiquitin-protein ligase 2 ;HECT, C2 and WW domain-containing protein 2 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with TP73.
Function:
E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MASSAREHLL | FVRRRNPQMR | YTLSPENLQS | LAAQSSMPEN | MTLQRANSDT |
100:
DLVTSESRSS | LTASMYEYTL | GQAQNLIIFW | DIKEEVDPSD | WIGLYHIDEN |
150:
SPANFWDSKN | RGVTGTQKGQ | IVWRIEPGPY | FMEPEIKICF | KYYHGISGAL |
200:
RATTPCITVK | NPAVMMGAEG | MEGGASGNLH | SRKLVSFTLS | DLRAVGLKKG |
250:
MFFNPDPYLK | MSIQPGKKSS | FPTCAHHGQE | RRSTIISNTT | NPIWHREKYS |
300:
FFALLTDVLE | IEIKDKFAKS | RPIIKRFLGK | LTIPVQRLLE | RQAIGDQMLS |
350:
YNLGRRLPAD | HVSGYLQFKV | EVTSSVHEDA | SPEAVGTILG | VNSVNGDLGS |
400:
PSDDEDMPGS | HHDSQVCSNG | PVSEDSAADG | TPKHSFRTSS | TLEIDTEELT |
450:
STSSRTSPPR | GRQDSLNDYL | DAIEHNGHSR | PGTATCSERS | MGASPKLRSS |
500:
FPTDTRLNAM | LHIDSDEEDH | EFQQDLGYPS | SLEEEGGLIM | FSRASRADDG |
550:
SLTSQTKLED | NPVENEEAST | HEAASFEDKP | ENLPELAESS | LPAGPAPEEG |
600:
EGGPEPQPSA | DQGSAELCGS | QEVDQPTSGA | DTGTSDASGG | SRRAVSETES |
650:
LDQGSEPSQV | SSETEPSDPA | RTESVSEAST | RPEGESDLEC | ADSSCNESVT |
700:
TQLSSVDTRC | SSLESARFPE | TPAFSSQEEE | DGACAAEPTS | SGPAEGSQES |
750:
VCTAGSLPVV | QVPSGEDEGP | GAESATVPDQ | EELGEVWQRR | GSLEGAAAAA |
800:
ESPPQEEGSA | GEAQGTCEGA | TAQEEGATGG | SQANGHQPLR | SLPSVRQDVS |
850:
RYQRVDEALP | PNWEARIDSH | GRIFYVDHVN | RTTTWQRPTA | PPAPQVLQRS |
900:
NSIQQMEQLN | RRYQSIRRTM | TNERPEENTN | AIDGAGEEAD | FHQASADFRR |
950:
ENILPHSTSR | SRITLLLQSP | PVKFLISPEF | FTVLHSNPSA | YRMFTNNTCL |
1000:
KHMITKVRRD | THHFERYQHN | RDLVGFLNMF | ANKQLELPRG | WEMKHDHQGK |
1050:
AFFVDHNSRT | TTFIDPRLPL | QSSRPTSALV | HRQHLTRQRS | HSAGEVGEDS |
1100:
RHAGPPVLPR | PSSTFNTVSR | PQYQDMVPVA | YNDKIVAFLR | QPNIFEILQE |
1150:
RQPDLTRNHS | LREKIQFIRT | EGTPGLVRLS | SDADLVMLLS | LFEEEIMSYV |
1200:
PPHALLHPSY | CQSPRGSPVS | SPQNSPGTQR | ANARAPAPYK | RDFEAKLRNF |
1250:
YRKLETKGYG | QGPGKLKLII | RRDHLLEDAF | NQIMGYSRKD | LQRNKLYVTF |
1300:
VGEEGLDYSG | PSREFFFLVS | RELFNPYYGL | FEYSANDTYT | VQISPMSAFV |
1350:
DNHHEWFRFS | GRILGLALIH | QYLLDAFFTR | PFYKALLRIL | CDLSDLEYLD |
1400:
EEFHQSLQWM | KDNDIHDILD | LTFTVNEEVF | GQITERELKP | GGANIPVTEK |
1450:
NKKEYIERMV | KWRIERGVVQ | QTESLVRGFY | EVVDARLVSV | FDARELELVI |
1500:
AGTAEIDLSD | WRNNTEYRGG | YHDNHIVIRW | FWAAVERFNN | EQRLRLLQFV |
1550:
TGTSSIPYEG | FASLRGSNGP | RRFCVEKWGK | ITALPRAHTC | FNRLDLPPYP |
1572:
SFSMLYEKLL | TAVEETSTFG | LE
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human E3 ubiquitin-protein ligase HECW2
ELISA Kit for Human E3 ubiquitin-protein ligase HECW2
CLIA Kit for Human E3 ubiquitin-protein ligase HECW2
CLIA Kit for Human E3 ubiquitin-protein ligase HECW2
Polyclonal Antibody for Human E3 ubiquitin-protein ligase HECW2
Polyclonal Antibody for Human E3 ubiquitin-protein ligase HECW2
Monoclonal Antibody for Human E3 ubiquitin-protein ligase HECW2
Monoclonal Antibody for Human E3 ubiquitin-protein ligase HECW2
Protein for Human E3 ubiquitin-protein ligase HECW2
Protein for Human E3 ubiquitin-protein ligase HECW2
R&D Technical Data
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Precision
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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Brain .
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1352-1572 (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH TP73;TISSUE SPECIFICITY
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cervix carcinoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]