Gene name:
HEY2 (BHLHB32;CHF1;GRL;HERP;HERP1;HRT2) ;
Protein name:
Hairy/enhancer-of-split related with YRPW motif protein 2 ;
Alternative:
Class B basic helix-loop-helix protein 32 (bHLHb32) ;Cardiovascular helix-loop-helix factor 1 (hCHF1) ;Hairy and enhancer of split-related protein 2 (HESR-2) ;HES-related repressor protein 2 ;Protein gridlock homolog ;Hairy-related transcription factor 2 (HRT-2;hHRT2) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
May self-associate (By similarity). Interacts with GATA4, HES1 and HEYL (By similarity). Interacts with HDAC1, NCOR1 and SIN3A (By similarity). Interacts with ARNT and GATA6.
Function:
Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MKRPCEETTS | ESDMDETIDV | GSENNYSGQS | TSSVIRLNSP | TTTSQIMARK |
100:
KRRGIIEKRR | RDRINNSLSE | LRRLVPTAFE | KQGSAKLEKA | EILQMTVDHL |
150:
KMLQATGGKG | YFDAHALAMD | FMSIGFRECL | TEVARYLSSV | EGLDSSDPLR |
200:
VRLVSHLSTC | ATQREAAAMT | SSMAHHHHPL | HPHHWAAAFH | HLPAALLQPN |
250:
GLHASESTPC | RLSTTSEVPP | AHGSALLTAT | FAHADSALRM | PSTGSVAPCV |
300:
PPLSTSLLSL | SATVHAAAAA | ATAAAHSFPL | SFAGAFPMLP | PNAAAAVAAA |
337:
TAISPPLSVS | ATSSPQQTSS | GTNNKPYRPW | GTEVGAF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Hairy/enhancer-of-split related with YRPW motif protein 2
ELISA Kit for Human Hairy/enhancer-of-split related with YRPW motif protein 2
CLIA Kit for Human Hairy/enhancer-of-split related with YRPW motif protein 2
CLIA Kit for Human Hairy/enhancer-of-split related with YRPW motif protein 2
Polyclonal Antibody for Human Hairy/enhancer-of-split related with YRPW motif protein 2
Polyclonal Antibody for Human Hairy/enhancer-of-split related with YRPW motif protein 2
Monoclonal Antibody for Human Hairy/enhancer-of-split related with YRPW motif protein 2
Monoclonal Antibody for Human Hairy/enhancer-of-split related with YRPW motif protein 2
Protein for Human Hairy/enhancer-of-split related with YRPW motif protein 2
Protein for Human Hairy/enhancer-of-split related with YRPW motif protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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Lung .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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