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Index > Protein center > Hhex(Gene name) > Mouse
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  • Hhex (Gene name),
  • Hematopoietically-expressed homeobox protein Hhex (Protein name ),  HHEX_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Hhex(Prh;Prhx);
    Protein name:
    Hematopoietically-expressed homeobox protein Hhex(Homeobox protein HEX;mHex);
    Alternative:
    Homeobox protein PRH;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    271
    Sequence:
    50:
    MQFPHPGPAA | APAVGVPLYA | PTPLLQPAHP | TPFYIDDILG | RGPAAPTPTP | 
    100:
    TLPSPNSSFT | SLVSSYRTPV | YEPTPVHPAF | SHHPAAALAA | AYGPSGFGGP | 
    150:
    LYPFPRTVND | YTHALLRHDP | LGKPLLWSPF | LQRPLHKRKG | GQVRFSNDQT | 
    200:
    VELEKKFETQ | KYLSPPERKR | LAKMLQLSER | QVKTWFQNRR | AKWRRLKQEN | 
    250:
    PQSNKKDALD | SLDTSCEQGQ | DLPSEQNKGA | SLDRSQCSPS | PASQEDPDSE | 
    271:
    ISEDSDQEVD | IEGDKGYFNA | G
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    KEGG:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Homeobox protein HEX
    ELISA Kit for Mouse Homeobox protein HEX
    ELISA Kit for Mouse Homeobox protein HEX
    CLIA Kit for Mouse Homeobox protein HEX
    CLIA Kit for Mouse Homeobox protein HEX
    CLIA Kit for Mouse Homeobox protein HEX
    Polyclonal Antibody for Mouse Homeobox protein HEX
    Polyclonal Antibody for Mouse Homeobox protein HEX
    Polyclonal Antibody for Mouse Homeobox protein HEX
    Monoclonal Antibody for Mouse Homeobox protein HEX
    Monoclonal Antibody for Mouse Homeobox protein HEX
    Monoclonal Antibody for Mouse Homeobox protein HEX
    Protein for Mouse Homeobox protein HEX
    Protein for Mouse Homeobox protein HEX
    Protein for Mouse Homeobox protein HEX

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "HEX: a novel homeobox gene expressed during haematopoiesis and conserved between mouse and human."
      Bedford F.K. , Ashworth A. , Enver T. , Wiedemann L.M.
      Nucleic Acids Res.21:1245-1249(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];TISSUE SPECIFICITY
      strain: C57BL/6J.
    2. 2.
      "Genomic organization and promoter analysis of a mouse homeobox gene, Hex."
      Myint Z. , Inazu T. , Tanaka T. , Yamada K. , Keng V.W. , Inoue Y. , Kuriyama M. , Noguchi T.
      J. Biochem.125:795-802(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129.
    3. 3.
      "Genomic structure, cDNA mapping, and chromosomal localization of the mouse homeobox gene, Hex."
      Ghosh B. , Jacobs H.C. , Wiedemann L.M. , Brown A. , Bedford F.K. , Nimmakayalu M.A. , Ward D.C. , Bogue C.W.
      Mamm. Genome10:1023-1025(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129.
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Cecum.
      tissue: Head.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Liver.
    6. 6.
      "Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function."
      Brickman J.M. , Jones C.M. , Clements M. , Smith J.C. , Beddington R.S.P.
      Development127:2303-2315(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal."
      Zamparini A.L. , Watts T. , Gardner C.E. , Tomlinson S.R. , Johnston G.I. , Brickman J.M.
      Development133:3709-3722(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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